FIGURE

Figure 1

ID

ZDB-FIG-251023-142

Publication

Ameen et al., 2025 - Mutation of the GDP-Fucose Biosynthesis Gene gmds Increases Hair Cell Number and Neuromast Regenerative Capacity in Zebrafish

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Figure 1

Abnormal fucosylation but normal neuromast morphology in gmds^−/−. Aleuria aurantia lectin staining for fucosylated proteins (A,B) is present on control (n = 20), but not gmds^−/− neuromasts (n = 14). Scanning electron microscope (SEM) image of the lateral line neuromasts at 5 dpf under homeostatic conditions in wild-type (n = 9) and gmds^−/− (n = 9) (C,D) with a higher magnification image of a supraorbital neuromast in (E,F).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gmds^nfl2/nfl2 (AB)
Observed In:	neuromast neuromast protein O-linked glycosylation via fucose neuromast hair cell
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

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