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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-970313-40
Tada, Masazumi
Email: m.tada@ucl.ac.uk
URL:
Affiliation: Tada Lab
Address: Department of Anatomy and Developmental Biology University College London Gower Street London, WC1E 6BT United Kingdom
Country: United Kingdom
Phone: 44-207-679-3330
Fax: 44-207-679-7349
Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS
Gastrulation movements in vertebrates; particularly regulation of convergent extension in the zebrafish embryo.


PUBLICATIONS
Anton, K.A., Kajita, M., Narumi, R., Fujita, Y., Tada, M. (2018) Src-transformed cells hijack mitosis to extrude from the epithelium. Nature communications. 9:4695
Smutny, M., Ákos, Z., Grigolon, S., Shamipour, S., Ruprecht, V., Čapek, D., Behrndt, M., Papusheva, E., Tada, M., Hof, B., Vicsek, T., Salbreux, G., Heisenberg, C.P. (2017) Friction forces position the neural anlage. Nature cell biology. 19(4):306-317
Saitoh, S., Maruyama, T., Yako, Y., Kajita, M., Fujioka, Y., Ohba, Y., Kasai, N., Sugama, N., Kon, S., Ishikawa, S., Hayashi, T., Yamazaki, T., Tada, M., Fujita, Y. (2017) Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells. Proceedings of the National Academy of Sciences of the United States of America. 114(12):E2327-E2336
Hernández-Bejarano, M., Gestri, G., Spawls, L., Nieto-López, F., Picker, A., Tada, M., Brand, M., Bovolenta, P., Wilson, S.W., Cavodeassi, F. (2015) Opposing Shh and Fgf signals initiate nasotemporal patterning of the retina. Development (Cambridge, England). 142(22):3933-42
Ramezani, T., Laux, D.W., Bravo, I.R., Tada, M., Feng, Y. (2015) Live Imaging of Innate Immune and Preneoplastic Cell Interactions Using an Inducible Gal4/UAS Expression System in Larval Zebrafish Skin. Journal of visualized experiments : JoVE. (96)
Kajita, M., Sugimura, K., Ohoka, A., Burden, J., Suganuma, H., Ikegawa, M., Shimada, T., Kitamura, T., Shindoh, M., Ishikawa, S., Yamamoto, S., Saitoh, S., Yako, Y., Takahashi, R., Okajima, T., Kikuta, J., Maijima, Y., Ishii, M., Tada, M., Fujita, Y. (2014) Filamin acts as a key regulator in epithelial defence against transformed cells. Nature communications. 5:4428
Lours-Calet, C., Alvares, L.E., El-Hanfy, A.S., Gandesha, S., Walters, E.H., Sobreira, D.R., Wotton, K.R., Jorge, E.C., Lawson, J.A., Kelsey Lewis, A., Tada, M., Sharpe, C., Kardon, G., Dietrich, S. (2014) Evolutionarily conserved morphogenetic movements at the vertebrate head-trunk interface coordinate the transport and assembly of hypopharyngeal structures. Developmental Biology. 390:231-46
Hori, A., Ikebe, C., Tada, M., and Toda, T. (2014) Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation. EMBO reports. 15(2):175-184
Lepage, S.E., Tada, M., and Bruce, A.E. (2014) Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly. Developmental Biology. 385(1):52-66
Lee, O., Takesono, A., Tada, M., Tyler, C.R., and Kudoh, T. (2012) Biosensor Zebrafish Provide New Insights into Potential Health Effects of Environmental Estrogens. Environmental health perspectives. 120(7):990-996
Mapp, O.M., Walsh, G.S., Moens, C.B., Tada, M., and Prince, V.E. (2011) Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity. Development (Cambridge, England). 138(10):2121-2132
Clark, M.D., Guryev, V., Bruijn, E., Nijman, I.J., Tada, M., Wilson, C., Deloukas, P., Postlethwait, J.H., Cuppen, E., and Stemple, D.L. (2011) Single nucleotide polymorphism (SNP) panels for rapid positional cloning in zebrafish. Methods in cell biology. 104:219-235
Oteiza, P., Köppen, M., Krieg, M., Pulgar, E., Farias, C., Melo, C., Preibisch, S., Müller, D., Tada, M., Hartel, S., Heisenberg, C.P., and Concha, M.L. (2010) Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ. Development (Cambridge, England). 137(20):3459-3468
May-Simera, H.L., Kai, M., Hernandez, V., Osborn, D.P., Tada, M., and Beales, P.L. (2010) Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish. Developmental Biology. 345(2):215-225
Kajita, M., Hogan, C., Harris, A.R., Dupre-Crochet, S., Itasaki, N., Kawakami, K., Charras, G., Tada, M., and Fujita, Y. (2010) Interaction with surrounding normal epithelial cells influences signalling pathways and behaviour of Src-transformed cells. Journal of Cell Science. 123(Pt 2):171-180
Tada, M., and Kai, M. (2009) Noncanonical Wnt/PCP Signaling During Vertebrate Gastrulation. Zebrafish. 6(1):29-40
Carreira-Barbosa, F., Kajita, M., Morel, V., Wada, H., Okamoto, H., Martinez Arias, A., Fujita, Y., Wilson, S.W., and Tada, M. (2009) Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development (Cambridge, England). 136(3):383-392
Kai, M., Heisenberg, C.P., and Tada, M. (2008) Sphingosine-1-phosphate receptors regulate individual cell behaviours underlying the directed migration of prechordal plate progenitor cells during zebrafish gastrulation. Development (Cambridge, England). 135(18):3043-3051
Tobin, J.L., Di Franco, M., Eichers, E., May-Simera, H., Garcia, M., Yan, J., Quinlan, R., Justice, M.J., Hennekam, R.C., Briscoe, J., Tada, M., Mayor, R., Burns, A.J., Lupski, J.R., Hammond, P., and Beales, P.L. (2008) Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome. Proceedings of the National Academy of Sciences of the United States of America. 105(18):6714-6719
Blanco, M.J., Barrallo-Gimeno, A., Acloque, H., Reyes, A.E., Tada, M., Allende, M.L., Mayor, R., and Nieto, M.A. (2007) Snail1a and Snail1b cooperate in the anterior migration of the axial mesendoderm in the zebrafish embryo. Development (Cambridge, England). 134(22):4073-4081
Beales, P.L., Bland, E., Tobin, J.L., Bacchelli, C., Tuysuz, B., Hill, J., Rix, S., Pearson, C.G., Kai, M., Hartley, J., Johnson, C., Irving, M., Elcioglu, N., Winey, M., Tada, M., and Scambler, P.J. (2007) IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy. Nature Genetics. 39(6):727-729
Tawk, M., Araya, C., Lyons, D.A., Reugels, A.M., Girdler, G.C., Bayley, P.R., Hyde, D.R., Tada, M., and Clarke, J.D. (2007) A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis. Nature. 446(7137):797-800
Caneparo, L., Huang, Y.L., Staudt, N., Tada, M., Ahrendt, R., Kazanskaya, O., Niehrs, C., and Houart, C. (2007) Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/betacatenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. Genes & Development. 21(4):465-480
Witzel, S., Zimyanin, V., Carreira-Barbosa, F., Tada, M., and Heisenberg, C.P. (2006) Wnt11 controls cell contact persistence by local accumulation of Frizzled 7 at the plasma membrane. The Journal of cell biology. 175(5):791-802
Ross, A.J., May-Simera, H., Eichers, E.R., Kai, M., Hill, J., Jagger, D.J., Leitch, C.C., Chapple, J.P., Munro, P.M., Fisher, S., Tan, P.L., Phillips, H.M., Leroux, M.R., Henderson, D.J., Murdoch, J.N., Copp, A.J., Eliot, M.M., Lupski, J.R., Kemp, D.T., Dollfus, H., Tada, M., Katsanis, N., Forge, A., and Beales, P.L. (2005) Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nature Genetics. 37(10):1135-1140
Cavodeassi, F., Carreira-Barbosa, F., Young, R., Concha, M., Allende, M.L., Houart, C., Tada, M., and Wilson, S. (2005) Early Stages of Zebrafish Eye Formation Require the Coordinated Activity of Wnt11, Fz5, and the Wnt/Catenin Pathway. Neuron. 47(1):43-56
Ulrich, F., Concha, M.L., Heid, P.J., Voss, E., Witzel, S., Roehl, H., Tada, M., Wilson, S.W., Adams, R.J., Soll, D.R., and Heisenberg, C.P. (2003) Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development (Cambridge, England). 130(22):5375-5384
Carreira-Barbosa, F., Concha, M.L., Takeuchi, M., Ueno, N., Wilson, S.W., and Tada, M. (2003) Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development (Cambridge, England). 130(17):4037-4046
Kilian, B., Mansukoski, H., Barbosa, F.C., Ulrich, F., Tada, M., and Heisenberg, C.P. (2003) The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. Mechanisms of Development. 120(4):467-476
Heisenberg, C.-P. and Tada, M. (2002) Zebrafish gastrulation movements: bridging cell and developmental biology. Seminars in cell & developmental biology. 13(6):471-479
Tada, M., Concha, M.I., and Heisenberg, C.-P. (2002) Non-canonical Wnt signalling and regulation of gastrulation movements. Seminars in cell & developmental biology. 13(3):251-260
Heisenberg, C.-P. and Tada, M. (2002) Wnt signalling: a moving picture emerges from van gogh. Current biology : CB. 12(4):R126-R128
Heisenberg, C.P., Tada, M., Rauch, G.J., Saude, L., Concha, M.L., Geisler, R., Stemple, D.L., Smith, J.C., and Wilson, S.W. (2000) Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature. 405(6782):76-81
Nagaso, H., Suzuki, A., Tada, M., and Ueno, N. (1999) Dual specificity of activin type II receptor ActRIIb in dorso-ventral patterning during zebrafish embryogenesis. Development, growth & differentiation. 41(2):119-133
Nikaido, M., Tada, M., and Ueno, N. (1999) Restricted expression of the receptor serine/threonine kinase BMPR-IB in zebrafish. Mechanisms of Development. 82(1-2):219-222
Nikaido, M., Tada, M., Takeda, H., Kuroiwa, A., and Ueno, N. (1999) In vivo analysis using variants of zebrafish BMPR-IA: range of action and involvement of BMP in ectoderm patterning. Development (Cambridge, England). 126:181-190
Laforest, L., Brown, C.W., Poleo, G., Géraudie, J., Tada, M., Ekker, M., and Akimenko, M.-A. (1998) Involvement of the Sonic hedgehog, patched 1, and bmp2 genes in patterning of the zebrafish dermal fin rays. Development (Cambridge, England). 125:4175-4184
Nikaido, M., Tada, M., Saji, T., and Ueno, N. (1997) Conservation of BMP signaling in zebrafish mesoderm patterning. Mechanisms of Development. 61(1-2):75-88

NON-ZEBRAFISH PUBLICATIONS
Heisenberg, C.P. and Tada, M. (2002) Wnt signalling: a moving picture emerges from van gogh. Curr. Biol. 12(4):R126-128.

Tada, M. and Smith, J.C. (2000) Xwnt11, a target of Xenopus Brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 127, 2227-2238.

Smith, J.C., Conlon, F.L.m, Saka, Y., and Tada, M. (2000) Xwnt11 and the regulation of gastrulation in Xenopus. Philos. Trans. R Soc. Lond. B Biol. Sci. 355(1399):923-930.

Saka, Y., Tada, M., and Smith, J.C. (2000) A screen for targets of Xenopus T-box gene Xbra. Mech. Dev. 93, 27-39.

Trindade, M., Tada, M., and Smith, J.C. (1999) DNA-binding specificity and embryological function of Xom (Xvent-2). Dev. Biol. 216, 442-456.

Casey, E.S., Tada, M., Fairclough, L., Wylie, C.C., Heasman, J., and Smith, J.C. (1999) Bix4 is activated by VegT and mediates endoderm formation in Xenopus development. Development 126, 4193-4200.

Tada, M., Casey, E.S., Fairclough, L., and Smith, J.C. (1998) Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm. Development 125, 3997-4006.

Tada, M., O'Reilly, M.A., and Smith, J.C. (1997) Analysis of competence and of Brachyury autoinduction by use of hormone-inducible Xbra. Development 124, 2225-2234.