|ZFIN ID: ZDB-PUB-020807-4|
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Non-canonical Wnt signalling and regulation of gastrulation movements
Tada, M., Concha, M.I., and Heisenberg, C.-P.
|Source:||Seminars in cell & developmental biology 13(3): 251-260 (Review)|
|Registered Authors:||Concha, Miguel, Heisenberg, Carl-Philipp, Tada, Masazumi|
|PubMed:||12137734 Full text @ Sem. Cell Dev. Biol.|
Tada, M., Concha, M.I., and Heisenberg, C.-P. (2002) Non-canonical Wnt signalling and regulation of gastrulation movements. Seminars in cell & developmental biology. 13(3):251-260.
ABSTRACTMembers of the Wnt family have been implicated in a variety of developmental processes including axis formation, patterning of the central nervous system and tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway similar to that involved in the establishment of planar cell polarity in Drosophila regulates convergent extension movements during zebrafish and Xenopus gastrulation. This finding provides a good starting point to dissect the complex cell biology and genetic regulation of vertebrate gastrulation movements.
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