|ZFIN ID: ZDB-PUB-030116-2|
Zebrafish gastrulation movements: bridging cell and developmental biology
Heisenberg, C.-P. and Tada, M.
|Source:||Seminars in cell & developmental biology 13(6): 471-479 (Review)|
|Registered Authors:||Heisenberg, Carl-Philipp, Tada, Masazumi|
|Keywords:||gastrulation; convergent extension; cell polarity; zebrafish|
|PubMed:||12468250 Full text @ Sem. Cell Dev. Biol.|
Heisenberg, C.-P. and Tada, M. (2002) Zebrafish gastrulation movements: bridging cell and developmental biology. Seminars in cell & developmental biology. 13(6):471-479.
ABSTRACTDuring vertebrate gastrulation, large cellular rearrangements lead to the formation of the three germ layers, ectoderm, mesoderm and endoderm. Zebrafish offer many genetic and experimental advantages for studying vertebrate gastrulation movements. For instance, several mutants, including silberblick, knypek and trilobite, exhibit defects in morphogenesis during gastrulation. The identification of the genes mutated in these lines together with the analysis of the mutant phenotypes has provided new insights into the molecular and cellular mechanisms that underlie vertebrate gastrulation movements.
- Genes / Markers (6)