ZFIN ID: ZDB-MRPHLNO-070328-5
Morpholino Name: MO1-dcc
Target: dcc (1)
Sequence:
5' - GAATATCTCCAGTGACGCAGCCCAT - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
TARGET LOCATION
No data available
CONSTRUCTS WITH SEQUENCES FROM MO1-dcc No data available
GENE EXPRESSION
Gene expression in Wild Types + MO1-dcc
Expressed Gene Anatomy Figures
dcc dorso-rostral cluster Fig. 7 from Zhang et al., 2012
robo2 dorso-rostral cluster Fig. 7 from Zhang et al., 2012
PHENOTYPE 
Phenotype resulting from MO1-dcc
Phenotype Figures
branching involved in lymph vessel morphogenesis process quality, abnormal Fig. 4 with image from Lim et al., 2011
commissural neuron axon guidance process quality, abnormal Fig. 4 with image from Sun et al., 2016
CoPA axon extension involved in axon guidance decreased process quality, abnormal Fig. 4 with image from Sun et al., 2016
CoPA neuron projection misrouted, abnormal Fig. 4 with image from Sun et al., 2016
dendrite development disrupted, abnormal Fig. 3 from Suli et al., 2006
dorso-rostral cluster axon extension process quality, abnormal Fig. 3 with imageFig. 4 with imageFig. 5 with image from Gao et al., 2012
Fig. 4 from Zhang et al., 2012
dorso-rostral cluster neuron projection mislocalised, abnormal Fig. 4 from Zhang et al., 2012
dorso-rostral cluster neuron projection mislocalised dorsally, abnormal Fig. 3 with imageFig. 4 with imageFig. 5 with image from Gao et al., 2012
dorso-rostral cluster neuron projection misrouted, abnormal Fig. 4 from Zhang et al., 2012
dorso-rostral cluster neuron projection multiple, abnormal Fig. 4 with image from Gao et al., 2012
dorso-rostral cluster neuron projection physical object quality, abnormal Fig. 3 with imageFig. 4 with imageFig. 5 with image from Gao et al., 2012
horizontal myoseptum lacks parts or has fewer parts of type RoP motor neuron axon, abnormal Fig. 6 with image from Lim et al., 2011
horizontal myoseptum lacks parts or has fewer parts of type motor neuron axon, abnormal Fig. 6 with image from Lim et al., 2011
lymph vessel development process quality, abnormal Fig. 4 with imageFig. S1 with image from Lim et al., 2011
olfactory bulb axon guidance disrupted, abnormal Fig. 3 from Lakhina et al., 2012
olfactory receptor cell axon attached to anterior commissure, abnormal Fig. 3 from Lakhina et al., 2012
olfactory receptor cell axon attached to lateral protoglomerulus 2, abnormal Fig. 3 from Lakhina et al., 2012
olfactory receptor cell axon attached to lateral protoglomerulus 1, abnormal Fig. 3 from Lakhina et al., 2012
olfactory receptor cell axon position, abnormal Fig. 3 from Lakhina et al., 2012
parachordal vessel immature, abnormal Fig. 4 with image from Lim et al., 2011
parachordal vessel venous endothelial cell migration involved in lymph vessel development arrested, abnormal Fig. 4 with image from Lim et al., 2011
thoracic duct aplastic, abnormal Fig. S1 with image from Lim et al., 2011
VaP motor neuron axon protruding into muscle pioneer, abnormal Fig. 5 with image from Hale et al., 2011

Phenotype of all Fish created by or utilizing MO1-dcc
Phenotype Fish Conditions Figures
VaP motor neuron axon protruding into muscle pioneer, abnormal WT + MO1-dcc standard conditions Fig. 5 with image from Hale et al., 2011
commissural neuron axon guidance process quality, abnormal WT + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
CoPA neuron projection misrouted, abnormal WT + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
CoPA axon extension involved in axon guidance decreased process quality, abnormal WT + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
lymph vessel development process quality, abnormal y1Tg/+ + MO1-dcc standard conditions Fig. 4 with imageFig. S1 with image from Lim et al., 2011
branching involved in lymph vessel morphogenesis process quality, abnormal y1Tg/+ + MO1-dcc standard conditions Fig. 4 with image from Lim et al., 2011
thoracic duct aplastic, abnormal y1Tg/+ + MO1-dcc standard conditions Fig. S1 with image from Lim et al., 2011
parachordal vessel immature, abnormal y1Tg/+ + MO1-dcc standard conditions Fig. 4 with image from Lim et al., 2011
parachordal vessel venous endothelial cell migration involved in lymph vessel development arrested, abnormal y1Tg/+ + MO1-dcc standard conditions Fig. 4 with image from Lim et al., 2011
dorso-rostral cluster neuron projection mislocalised, abnormal b1204Tg + MO1-dcc standard conditions Fig. 4 from Zhang et al., 2012
dorso-rostral cluster neuron projection physical object quality, abnormal b1204Tg + MO1-dcc standard conditions Fig. 3 with imageFig. 4 with imageFig. 5 with image from Gao et al., 2012
dorso-rostral cluster neuron projection multiple, abnormal b1204Tg + MO1-dcc standard conditions Fig. 4 with image from Gao et al., 2012
dorso-rostral cluster neuron projection mislocalised dorsally, abnormal b1204Tg + MO1-dcc standard conditions Fig. 3 with imageFig. 4 with imageFig. 5 with image from Gao et al., 2012
dorso-rostral cluster axon extension process quality, abnormal b1204Tg + MO1-dcc standard conditions Fig. 3 with imageFig. 4 with imageFig. 5 with image from Gao et al., 2012
Fig. 4 from Zhang et al., 2012
dorso-rostral cluster neuron projection misrouted, abnormal b1204Tg + MO1-dcc standard conditions Fig. 4 from Zhang et al., 2012
horizontal myoseptum lacks parts or has fewer parts of type RoP motor neuron axon, abnormal ml2Tg + MO1-dcc standard conditions Fig. 6 with image from Lim et al., 2011
horizontal myoseptum lacks parts or has fewer parts of type motor neuron axon, abnormal ml2Tg + MO1-dcc standard conditions Fig. 6 with image from Lim et al., 2011
dendrite development disrupted, abnormal rw0Tg + MO1-dcc standard conditions Fig. 3 from Suli et al., 2006
olfactory receptor cell axon attached to lateral protoglomerulus 2, abnormal p200Tg; p201Tg + MO1-dcc standard conditions Fig. 3 from Lakhina et al., 2012
olfactory receptor cell axon attached to lateral protoglomerulus 1, abnormal p200Tg; p201Tg + MO1-dcc standard conditions Fig. 3 from Lakhina et al., 2012
olfactory receptor cell axon position, abnormal p200Tg; p201Tg + MO1-dcc standard conditions Fig. 3 from Lakhina et al., 2012
olfactory bulb axon guidance disrupted, abnormal p200Tg; p201Tg + MO1-dcc standard conditions Fig. 3 from Lakhina et al., 2012
olfactory receptor cell axon attached to anterior commissure, abnormal p200Tg; p201Tg + MO1-dcc standard conditions Fig. 3 from Lakhina et al., 2012
olfactory receptor cell axon detached from lateral protoglomerulus 1, abnormal p201Tg; p202Tg + MO1-dcc standard conditions Fig. 7 from Lakhina et al., 2012
olfactory receptor cell axon attached to medial protoglomerulus, abnormal p201Tg; p202Tg + MO1-dcc standard conditions Fig. 4 from Lakhina et al., 2012
olfactory receptor cell axon attached to dorsal zone olfactory bulb, abnormal p201Tg; p202Tg + MO1-dcc standard conditions Fig. 4 from Lakhina et al., 2012
olfactory bulb axon guidance disrupted, abnormal p201Tg; p202Tg + MO1-dcc standard conditions Fig. 4Fig. 7 from Lakhina et al., 2012
olfactory receptor cell axon position, abnormal p201Tg; p202Tg + MO1-dcc standard conditions Fig. 4Fig. 7 from Lakhina et al., 2012
olfactory receptor cell axon attached to lateral zone olfactory bulb, abnormal p201Tg; p202Tg + MO1-dcc standard conditions Fig. 7 from Lakhina et al., 2012
olfactory receptor cell axon posterior to olfactory bulb, abnormal p201Tg; p202Tg + MO1-dcc standard conditions Fig. 7 from Lakhina et al., 2012
CoPA anterior/posterior axon guidance decreased process quality, abnormal fzd3arw689/rw689 + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
CoPA neuron projection misrouted, abnormal fzd3arw689/rw689 + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
commissural neuron axon guidance process quality, abnormal fzd3arw689/rw689 + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
axonal fasciculation decreased occurrence, abnormal robo2ti272z/ti272z + MO1-dcc standard conditions Fig. 5 from Kastenhuber et al., 2009
CoPA anterior/posterior axon guidance decreased process quality, abnormal scribrw468/rw468 + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
CoPA neuron projection misrouted, abnormal scribrw468/rw468 + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
commissural neuron axon guidance process quality, abnormal scribrw468/rw468 + MO1-dcc standard conditions Fig. 4 with image from Sun et al., 2016
parachordal vessel immature, abnormal y1Tg/+ + MO1-dcc + MO3-plcg1 standard conditions Fig. 4 with image from Lim et al., 2011
parachordal vessel venous endothelial cell migration involved in lymph vessel development arrested, abnormal y1Tg/+ + MO1-dcc + MO3-plcg1 standard conditions Fig. 4 with image from Lim et al., 2011
branching involved in lymph vessel morphogenesis process quality, abnormal y1Tg/+ + MO1-dcc + MO3-plcg1 standard conditions Fig. 4 with image from Lim et al., 2011
dorso-rostral cluster neuron projection mislocalised dorsally, abnormal b1204Tg + MO1-dcc + MO2-neo1a standard conditions Fig. 5 with image from Gao et al., 2012
dorso-rostral cluster axon extension process quality, abnormal b1204Tg + MO1-dcc + MO2-neo1a standard conditions Fig. 5 with image from Gao et al., 2012
dorso-rostral cluster neuron projection mislocalised dorsally, abnormal b1204Tg + MO1-dcc + MO1-ntn1b + MO4-ntn1a standard conditions Fig. 5 with image from Gao et al., 2012
dorso-rostral cluster neuron projection physical object quality, abnormal b1204Tg + MO1-dcc + MO1-ntn1b + MO4-ntn1a standard conditions Fig. 5 with image from Gao et al., 2012
dorso-rostral cluster axon extension process quality, abnormal b1204Tg + MO1-dcc + MO1-ntn1b + MO4-ntn1a standard conditions Fig. 5 with image from Gao et al., 2012
OTHER MO1-dcc MORPHOLINO PAGESNo links to external sites
CITATIONS (10)