ZFIN ID: ZDB-GENE-011101-2
Gene Name: DCC netrin 1 receptor
Gene Symbol: dcc
Sequence Ontology ID : SO:0000704

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Previous Names: spaced out, spo, zdcc (1)

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 19 figures from 11 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  brain, CaP motoneuron, cerebellum, diencephalon (all 47) expand
PHENOTYPE
Data: 15 figures from 9 publications
Observed in: anterior commissure, branching involved in lymph vessel morphogenesis, commissural neuron axon guidance, CoPA axon extension involved in axon guidance (all 27) expand
DISEASE ASSOCIATED WITH dcc HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
colorectal cancer Colorectal cancer, somatic 114500
esophageal cancer Esophageal carcinoma, somatic 133239
Mirror movements 1 157600
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior/posterior axon guidance (more)
Cellular Component integral component of membrane (more)
Molecular Function netrin receptor activity involved in chemoattraction (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR009138 (1)
  • InterPro:IPR010560 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR021157 (1)
  • InterPro:IPR033012 (1)
  • InterPro:IPR036116 (1)
  • InterPro:IPR036179 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF06583 (1)
  • Pfam:PF07679 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dcc
    Tg(10xUAS:dcc,myl7:EGFP)
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034985 (1) 4266bp
    Genomic GenBank:CABZ01088906 (1) 22627bp
    Polypeptide UniProtKB:Q49BB0 (1) 1421aa
    Sequence Clusters UniGene:121163 (1)
    Sequence Information (all 39)
    OTHER dcc GENE PAGES
  • Alliance (1)
  • Gene:569360 (1)
  • ORTHOLOGY for dcc (Chr: 5)
    CITATIONS (31)