FIGURE

Figure 5

ID

ZDB-FIG-221008-33

Publication

Xing et al., 2022 - Expression of myelin transcription factor 1 and lamin B receptor mediate neural progenitor fate transition in the zebrafish spinal cord pMN domain

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Figure 5

Lineage and transcription factor analysis for motor neuron and OPC lineages.A, monocle showing the putative developmental processes of progenitors or precursors in the pMN domain. Each dot represents an individual cell. Bifurcation of pMN progenitors into motor neuron (2) and OPC (11) lineages is shown. B, cells in (A) are shown in pseudotime. C, the temporal distribution of progenitors or precursors in the pMN domain. D, expression of known markers along the motor neuron or OPC lineage ordered in pseudotime. Note that isl1, mnx1, and neurod1 are enriched in the motor neuron branch, but nkx2.2a, olig1, sox10 are enriched in the OPC branch. E, heatmaps of the most differentially expressed transcription factors prebranching, in the motor neuron and OPC lineages. The color red denotes upregulation; blue denotes downregulation of genes. OPC, oligodendrocyte progenitor cell.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Biol. Chem.