Figure 5
- ID
- ZDB-FIG-201012-97
- Publication
- Heger et al., 2020 - The genetic factors of bilaterian evolution
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Two consensus phylogenetic trees showing the relationship of major metazoan lineages. The five factors of the Nodal signalling pathway (Nodal, Lefty, EGF-CFC, FoxH1, and Eomes) are displayed as coloured boxes. Their phylogenetic distribution and inferred evolutionary origin are mapped onto the tree. Gene births are indicated as coloured boxes above the respective branch. Inferred losses are represented by crosses. Bold labels to the left of a branch indicate branch ancestors: B = Bilateria, Eu = Eumetazoa, M = Metazoa. (A) Previous results regarding the evolution of Nodal pathway genes, as known from the literature. (B) Revised evolutionary history of the Nodal pathway genes according to our results. Note that none of the five factors has been found in arthropods and nematodes. The ecdysozoan boxes for Eomes and FoxH1 are derived from the presence of the genes in a single priapulid species. Grey shading: Hypothetical emergence of a putative kernel for mesoderm specification and neural patterning. |