Figure 4—figure supplement 1.

Exemplary multiple sequence alignments of three arthropod-specific orthogroups without known domains.

Top: View of a 194 AA alignment of OG_26631 with 36 sequences from 2 chelicerate, 1 myriapod, 2 crustacean, and 23 hexapod species. Center: View of a 165 AA alignment of OG_34551 with 28 sequences from 4 chelicerate, 1 myriapod, 2 crustacean, and 19 hexapod species. Bottom: View of a 155 AA alignment of OG_35928 with 27 sequences from 2 chelicerate, 1 myriapod, and 21 hexapod species. The alignments illustrate the existence of domain-like conservation patterns despite the absence of known protein domains. Short stretches of unaligned sequences were removed for clarity. Colouring of amino acids reflects chemical similarity (UGENE standard colour scheme; Okonechnikov et al., 2012). Bar chart on top displays sequence conservation of alignment columns beneath. Additional HMM-HMM searches suggest that the conserved regions constitute protein domains restricted to arthropods (Supplementary file 1–Supplementary Table 13).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife