ZFIN ID: ZDB-FIG-181108-25
Matsuda et al., 2017 - Thyroid Hormone Coordinates Pancreatic Islet Maturation During the Zebrafish Larval to Juvenile Transition to Maintain Glucose Homeostasis. Diabetes   66(10):2623-2635 Full text @ Diabetes
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage: Days 30-44
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Days 30-44

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
arxa wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism RTPCR
EGFP bns91Tg ; wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism IFL
gcga wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism RTPCR
GFP wprt8Tg ; ia1Tg control Days 30-44 islet IFL
wprt8Tg ; ia1Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 islet IFL
wprt8Tg ; zf5Tg control Days 30-44 islet IFL
wprt8Tg ; zf5Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 islet IFL
ins wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism RTPCR
mnx1 wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism RTPCR
neurod1 wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism RTPCR
pax4 wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism RTPCR
pax6b wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
bns91Tg ; wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism EGFP expression decreased amount, abnormal
wprt8Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 whole organism pax6b expression decreased amount, abnormal
Days 30-44 whole organism mnx1 expression decreased amount, abnormal
Days 30-44 whole organism ins expression decreased amount, abnormal
Days 30-44 whole organism neurod1 expression decreased amount, abnormal
Days 30-44 whole organism pax4 expression decreased amount, abnormal
Days 30-44 whole organism gcga expression increased amount, abnormal
Days 30-44 whole organism arxa expression increased amount, abnormal
Days 30-44 whole organism glucose increased amount, abnormal
wprt8Tg ; ia1Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 islet GFP expression increased amount, abnormal
wprt8Tg ; zf5Tg chemical ablation: thyroid follicle, chemical treatment by environment: metronidazole Days 30-44 islet GFP expression decreased amount, abnormal
Full text @ Diabetes