ZFIN ID: ZDB-GENE-001031-1
Gene Name: paired box 6b
Gene Symbol: pax6b
Sequence Ontology ID : SO:0000704

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Previous Names: Pax6.2, cb566 (1), fc09c10, id:ibd5095 (1), sri(l), wu:fc09c10 (1), wu:fc33g08

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 75 figures from 48 publications
Directly Submitted Expression Data: 6 figures (36 images) from Thisse et al., 2004 [MGC:92546]
  3 figures (4 images) from Kudoh et al., 2001 [ibd5095]
  6 figures (10 images) from Thisse et al., 2001 [cb566]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE
Data: 15 figures from 8 publications
Observed in:
DISEASE ASSOCIATED WITH pax6b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
aniridia Aniridia 106210
Cataract with late-onset corneal dystrophy 106210
coloboma ?Coloboma, ocular 120200
coloboma of optic nerve ?Coloboma of optic nerve 120430
?Morning glory disc anomaly 120430
Peters anomaly Anterior segment dysgenesis 5, multiple subtypes 604229
Foveal hypoplasia 1 136520
Optic nerve hypoplasia 165550
Keratitis 148190
DISEASE ASSOCIATED WITH pax6b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of transcription by RNA polymerase II (more)
Cellular Component nucleus (more)
Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific (more)
GO Terms (all 19)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001523 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR036388 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00034 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS51057 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF00292 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pax6b-001 (1) 4993
    ncRNA pax6b-002 (1) 1598
    mRNA pax6b-003 (1) 557
    pax6b-004 (1) 394
    pax6b-005 (1) 578
    ncRNA pax6b-006 (1) 683
    pax6b-007 (1) 681
    pax6b-008 (1) 830
    mRNA pax6b-009 (1) 571
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pax6b
    MARKER RELATIONSHIPS
    pax6bContained in: [BAC] DKEY-157G7 (1) (order this)
    pax6bContains: [SNP] rs3728027 (1), rs3728028 (1)
    pax6bEncodes: [EST] cb566 (1) (order this), fc09c10, fc33g08, ibd5095 (order this)
    [cDNA] MGC:92546 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131641 (1) 1733bp
    Genomic GenBank:BX000453 (1) 163585bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IQL7 (1) 450aa
    Sequence Clusters UniGene:132861 (1)
    Sequence Information (all 39)
    OTHER pax6b GENE PAGES
  • Alliance (1)
  • Gene:60639 (1)
  • VEGA:OTTDARG00000018846 (1)
  • Ensembl(GRCz11):ENSDARG00000045936 (1)
  • ORTHOLOGY for pax6b (Chr: 7)
    CITATIONS (118)