Gene

mnx1

ID
ZDB-GENE-040409-1
Name
motor neuron and pancreas homeobox 1
Symbol
mnx1 Nomenclature History
Previous Names
  • Hb9 (1)
  • hlxb9 (1)
  • zgc:112174
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity. Involved in spinal cord motor neuron cell fate specification and type B pancreatic cell differentiation. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; endoderm; mesoderm; neurons; and pancreatic system. Human ortholog(s) of this gene implicated in Currarino syndrome. Orthologous to human MNX1 (motor neuron and pancreas homeobox 1).
Genome Resources
Note
None
Expression
All Expression Data
31 figures from 19 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mnx1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Currarino syndrome Alliance Currarino syndrome 176450
Associated With mnx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Family IPR042768 Homeobox protein MNX1/Ceh-12
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily Homeobox protein MNX1/Ceh-12
UniProtKB:Q0VIL4 294
UniProtKB:Q6SYZ1 311
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations