ZFIN ID: ZDB-GENE-990415-15
Gene Name: aristaless related homeobox a
Gene Symbol: arxa
Sequence Ontology ID : SO:0000704

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Previous Names: arx, etID309855.24 (1), phox2a

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sequence-specific DNA binding activity; involved in animal organ development, nervous system development, and pancreatic A cell development; predicted to localize to the nucleus;  ...
GENE EXPRESSION
All Expression Data: 45 figures from 22 publications
Directly Submitted Expression Data: 6 figures (22 images) from Thisse et al., 2005 [eu265]
  4 figures (20 images) from Rauch et al., 2003 [fq33g07]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: 4 figures from 3 publications
Observed in:
DISEASE ASSOCIATED WITH arxa HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
early infantile epileptic encephalopathy 1 Epileptic encephalopathy, early infantile, 1 308350
lissencephaly Hydranencephaly with abnormal genitalia 300215
Lissencephaly, X-linked 2 300215
Partington syndrome Partington syndrome 309510
Proud syndrome 300004
Mental retardation, X-linked 29 and others 300419
DISEASE ASSOCIATED WITH arxa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neuron development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR003654 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS50803 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03826 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arxa-001 (1) 1522
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM arxa
    MARKER RELATIONSHIPS
    arxaContained in: [BAC] DKEY-162H1 (1) (order this)
    arxaEncodes: [EST] eu265 (1), fq33g07 (1) (order this)
    [cDNA] MGC:195292 (1) (order this), MGC:195299 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131384 (1) 1414bp
    Genomic GenBank:BX470095 (1) 209513bp Blast at MegaBLAST
    Polypeptide UniProtKB:B3DKI9 (1) 453aa
    Sequence Clusters UniGene:9011 (1)
    Sequence Information (all 24)
    OTHER arxa GENE PAGES
  • Alliance (1)
  • Gene:30657 (1)
  • VEGA:OTTDARG00000021352 (1)
  • Ensembl(GRCz11):ENSDARG00000058011 (2)
  • ORTHOLOGY for arxa (Chr: 24)
    CITATIONS (51)