ZFIN ID: ZDB-GENE-010219-1
Gene Name: glucagon a
Gene Symbol: gcga
Sequence Ontology ID : SO:0000704

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Previous Names: gcg (1), GLP-1 (1), glu, zgc:103616

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits glucagon receptor binding activity; involved in response to starvation and type B pancreatic cell development; predicted to localize to the extracellular region; orthologous to human GCG  ...
GENE EXPRESSION
All Expression Data: 89 figures from 47 publications
Directly Submitted Expression Data: 7 figures (8 images) from Thisse et al., 2004 [MGC:103616]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43786 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gcga HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    [?Hyperproglucagonemia]
    DISEASE ASSOCIATED WITH gcga VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to starvation (more)
    Cellular Component extracellular region (more)
    Molecular Function glucagon receptor binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000532 (1)
  • InterPro:IPR015550 (1)
  • PROSITE:PS00260 (1)
  • Pfam:PF00123 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gcga-201 (1) 1766
    gcga-202 (1) 820
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gcga
    MARKER RELATIONSHIPS
    gcgaContained in: [BAC] CH73-2D23 (1) (order this)
    [Fosmid] CH1073-467M9 (1) (order this)
    gcgaEncodes: [cDNA] MGC:103616 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001008595 (1) 1781bp
    Genomic GenBank:CU570889 (1) 52554bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IS85 (1) 176aa
    Sequence Clusters UniGene:83039 (1)
    Sequence Information (all 18)
    OTHER gcga GENE PAGES
  • Alliance (1)
  • Gene:494052 (1)
  • VEGA:OTTDARG00000029115 (1)
  • Ensembl(GRCz11):ENSDARG00000079296 (2)
  • ORTHOLOGY for gcga (Chr: 22)
    CITATIONS (89)