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Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-180723-3
Wang et al., 2017 - Identification of a new adtrp1-tfpi regulatory axis for the specification of primitive myelopoiesis and definitive hematopoiesis.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology   32(1):183-194 Full text @ FASEB J.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Prim-15 to Day 5
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-15 to Day 5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
GFP zf289Tg ; is5Tg standard conditions Long-pec hematopoietic stem cell IFL
Protruding-mouth hematopoietic stem cell IFL
zf289Tg ; is5Tg + MO1-adtrp1 standard conditions Long-pec hematopoietic stem cell IFL
Protruding-mouth hematopoietic stem cell IFL
lcp1 WT control Long-pec granulocyte monocyte progenitor cell ISH
WT + MO1-adtrp1 standard conditions Long-pec granulocyte monocyte progenitor cell ISH
mCherry zf289Tg ; is5Tg standard conditions Long-pec dorsal aorta endothelial cell IFL
Protruding-mouth dorsal aorta endothelial cell IFL
zf289Tg ; is5Tg + MO1-adtrp1 standard conditions Long-pec dorsal aorta endothelial cell IFL
Protruding-mouth dorsal aorta endothelial cell IFL
mpx WT control Long-pec granulocyte monocyte progenitor cell ISH
WT + MO1-adtrp1 standard conditions Long-pec granulocyte monocyte progenitor cell ISH
myb WT control Prim-15 hematopoietic stem cell ISH
WT + MO1-adtrp1 standard conditions Prim-15 hematopoietic stem cell ISH
rag1 WT control Day 5 lymphocyte ISH
WT + MO1-adtrp1 standard conditions Day 5 Not Detected lymphocyte ISH
runx1 WT control Prim-15 hematopoietic stem cell ISH
WT + MO1-adtrp1 standard conditions Prim-15 hematopoietic stem cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-adtrp1 standard conditions Prim-15 hematopoietic stem cell myb expression decreased amount, abnormal
Prim-15 hematopoietic stem cell runx1 expression decreased amount, abnormal
Long-pec granulocyte monocyte progenitor cell mpx expression decreased amount, abnormal
Long-pec granulocyte monocyte progenitor cell lcp1 expression decreased amount, abnormal
Long-pec nucleate erythrocyte hemoglobin complex decreased amount, abnormal
Day 5 lymphocyte rag1 expression absent, abnormal
zf289Tg ; is5Tg + MO1-adtrp1 standard conditions Long-pec hematopoietic stem cell GFP expression decreased amount, abnormal
Protruding-mouth apoptotic process increased occurrence, abnormal
Protruding-mouth hematopoietic stem cell GFP expression decreased amount, abnormal
Full text @ FASEB J.