ZFIN ID: ZDB-GENE-990415-234
Gene Name: recombination activating gene 1
Gene Symbol: rag1
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: etID309719.25 (1), recombinase

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
AUTOMATED DESCRIPTION
GENE EXPRESSION
All Expression Data: 190 figures from 129 publications
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu1999 Point Mutation Unknown Premature Stop ENU
sa32518 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • t26683 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • zf2024 Indel Unknown Unknown TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 11 figures from 5 publications
    Observed in:
    DISEASE ASSOCIATED WITH rag1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Omenn syndrome Omenn syndrome 603554
    severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive Severe combined immunodeficiency, B cell-negative 601457
    Combined cellular and humoral immune defects with granulomas 233650
    Alpha/beta T-cell lymphopenia with gamma/delta T-cell expansion, severe cytomegalovirus infection, and autoimmunity 609889
    DISEASE ASSOCIATED WITH rag1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein-DNA complex assembly (more)
    Cellular Component DNA recombinase complex (more)
    Molecular Function magnesium ion binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001841 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR017907 (1)
  • InterPro:IPR018957 (1)
  • InterPro:IPR019485 (1)
  • InterPro:IPR023336 (1)
  • InterPro:IPR024627 (1)
  • InterPro:IPR035714 (1)
  • PROSITE:PS00518 (1)
  • PROSITE:PS50089 (1)
  • PROSITE:PS51487 (1)
  • PROSITE:PS51765 (1)
  • Pfam:PF00097 (1)
  • Pfam:PF12560 (1)
  • Pfam:PF12940 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rag1-001 (1) 4485
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM rag1
    MARKER RELATIONSHIPS
    rag1Contained in: [BAC] CH211-256A21 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131389 (1) 3174bp
    Genomic GenBank:AL935203 (1) 163572bp
    Select Tool
    Polypeptide UniProtKB:F1QD74 (1) 1057aa
    Sequence Clusters UniGene:133607 (1)
    Sequence Information (all 21)
    OTHER rag1 GENE PAGES
  • Alliance (1)
  • Gene:30663 (1)
  • VEGA:OTTDARG00000027105 (1)
  • Ensembl(GRCz11):ENSDARG00000052122 (2)
  • ORTHOLOGY for rag1 (Chr: 25)
    CITATIONS (257)