ZFIN ID: ZDB-GENE-991213-5
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Gene Name: lymphocyte cytosolic protein 1 (L-plastin)
Gene Symbol: lcp1
Sequence Ontology ID : SO:0000704

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Previous Names: cb245 (1), fj24b12, l plastin, L-plastin (1), leucocyte-specific plastin, wu:fj24b12

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have actin filament binding activity; predicted to be involved in actin filament bundle assembly and actin filament network formation; localizes to the cytoplasm; orthologous to human  ...
GENE EXPRESSION
All Expression Data: 182 figures from 135 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2001 [cb245]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa45867 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • ud1 Indel Exon 2 Frameshift, Premature Stop CRISPR
    ud2 Indel Exon 2 Frameshift, Premature Stop CRISPR
    ud3 Small Deletion Exon 2 Frameshift, Premature Stop CRISPR
    Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Kell et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH lcp1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lcp1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament bundle assembly (more)
    Cellular Component cytoplasm (more)
    Molecular Function actin binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001589 (1)
  • InterPro:IPR001715 (1)
  • InterPro:IPR002048 (1)
  • InterPro:IPR011992 (1)
  • InterPro:IPR018247 (1)
  • InterPro:IPR036872 (1)
  • InterPro:IPR039953 (1)
  • InterPro:IPR039959 (1)
    		•
  • PROSITE:PS00018 (1)
  • PROSITE:PS00019 (1)
  • PROSITE:PS00020 (1)
  • PROSITE:PS50021 (1)
  • PROSITE:PS50222 (1)
    		•
  • Pfam:PF00307 (1)
  • Pfam:PF13499 (1)
    		•
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lcp1
    MARKER RELATIONSHIPS
    lcp1Contained in: [Fosmid] ZFOS-1926B4 (1)
    lcp1Encodes: [EST] cb245 (1) (order this), fj24b12
    [cDNA] MGC:66040 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131320 (1) 2324bp
    Select Tool
    Genomic GenBank:CU914623 (1) 37492bp
    Select Tool
    Polypeptide UniProtKB:A0A140LGK1 (1) 624aa
    Select Tool
    Sequence Clusters UniGene:25823 (1)
    Sequence Information (all 19)
    OTHER lcp1 GENE PAGES
  • Alliance (1)
  • Gene:30583 (1)
  • Ensembl(GRCz11):ENSDARG00000023188 (2)
    • ORTHOLOGY for lcp1 (Chr: 9)
    CITATIONS (223)