ZFIN ID: ZDB-GENE-000605-1
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Gene Name: runt-related transcription factor 1
Gene Symbol: runx1
Sequence Ontology ID : SO:0000704

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Previous Names: runx1a (1), runxa, aml1 (1)

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
GENE EXPRESSION
All Expression Data: 279 figures from 138 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hg1 Point Mutation Exon 4 Premature Stop ENU
zko52a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 22 figures from 15 publications
    Observed in:
    DISEASE ASSOCIATED WITH runx1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia Leukemia, acute myeloid 601626
    Platelet disorder, familial, with associated myeloid malignancy 601399
    DISEASE ASSOCIATED WITH runx1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process myeloid cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 24)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000040 (1)
  • InterPro:IPR008967 (1)
  • InterPro:IPR012346 (1)
  • InterPro:IPR013524 (1)
  • InterPro:IPR013711 (1)
  • InterPro:IPR016554 (1)
  • InterPro:IPR027384 (1)
    		•
  • PROSITE:PS51062 (1)
    		•
  • Pfam:PF00853 (1)
  • Pfam:PF08504 (1)
    		•
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM runx1
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131603 (1) 2543bp
    Select Tool
    Genomic GenBank:CABZ01057246 (1) 10349bp
    Select Tool
    Polypeptide UniProtKB:Q9DGB8 (1) 451aa
    Select Tool
    Sequence Clusters UniGene:82592 (1)
    Sequence Information (all 18)
    OTHER runx1 GENE PAGES
  • Alliance (1)
  • Gene:58126 (1)
  • Ensembl(GRCz11):ENSDARG00000087646 (1)
    • ORTHOLOGY for runx1 (Chr: 1)
    CITATIONS (230)