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General Information
ZIRC
ZFIN ID: ZDB-GENE-000605-1
Gene Name: RUNX family transcription factor 1
Gene Symbol: runx1
Sequence Ontology ID : SO:0000704

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Previous Names: runx1a (1), runxa, aml1 (1)

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits sequence-specific DNA binding activity. Involved in several processes, including endothelial to hematopoietic transition; hemopoiesis; and positive regulation of neutrophil differentiation.  ...
GENE EXPRESSION
All Expression Data: 312 figures from 148 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hg1 Point Mutation Exon 4 Premature Stop ENU
zko52a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH runx1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia Leukemia, acute myeloid 601626
    Platelet disorder, familial, with associated myeloid malignancy 601399
    DISEASE ASSOCIATED WITH runx1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process myeloid cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 24)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    MARKER RELATIONSHIPSNo data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131603 (1) 2543bp
    Genomic GenBank:CABZ01057246 (1) 10349bp
    Polypeptide UniProtKB:Q9DGB8 (1) 451aa
    Sequence Clusters UniGene:82592 (1)
    Sequence Information (all 18)
    OTHER runx1 GENE PAGES
  • Alliance (1)
  • Gene:58126 (1)
  • Ensembl(GRCz11):ENSDARG00000087646 (1)
  • ORTHOLOGY for runx1 (Chr: 1)
    CITATIONS (237)