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General Information
ZFIN ID: ZDB-FIG-140321-9
Miller et al., 2000 - sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development. Development (Cambridge, England)   127(17):3815-3828
Observed In:
Stage: Day 4

Fig. 1 suc mutants have reduced ventral cartilages. (A,B) Lateral views of live wild-type (A) and sucker mutant (B) larvae at 4 days. Mutants lack lower jaws and do not form swim bladders (asterisk in A). (C,D) Alcian-stained cartilages from a wild type (C) and suc mutant (D) dissected from the arches and flat-mounted. In wild types, dorsal and ventral elements in the first arch (pq, palatoquadrate; M, Meckel’s) and second arch (hs, hyosymplectic; ch, ceratohyal) are separated by joints (arrows). In mutants, ventral cartilages are reduced and fused to dorsal cartilages at what we interpret to be the sites of the missing joints (arrows). Scale bars: 100 μm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
edn1tf216b/tf216b standard conditions Day 4 embryonic viscerocranium morphogenesis decreased process quality, abnormal
Day 4 hyosymplectic cartilage fused with ceratohyal cartilage, abnormal
Day 4 palatoquadrate cartilage fused with Meckel's cartilage, abnormal
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright.