FIGURE

Fig. 4

ID

ZDB-FIG-120905-40

Publication

Bräutigam et al., 2011 - Vertebrate-specific glutaredoxin is essential for brain development

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Fig. 4

Formation of the axonal network depends on oxidoreductase activity of zfGrx2. Impaired formation of an axonal network (antiacetylated tubulin antibodies) could be rescued by injection of 20 pg/embryo capped zfGrx2 mRNA simultaneously to morpholino injection. Injection of mRNA coding for active site mutants of zfGrx2 (zfGrx2C37S, zfGrx2C40S) did not rescue. Scale bar, 50 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-glrx2
Knockdown Reagent:	MO1-glrx2
Observed In:	central nervous system development
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA