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ZFIN ID: ZDB-FIG-110712-1
Slagle et al., 2011 - Nodal-Dependent Mesendoderm Specification Requires the Combinatorial Activities of FoxH1 and Eomesodermin. PLoS Genetics   7(5):e1002072 Full text @ PLoS Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Prim-5
PHENOTYPE:
Fish:
Observed In:
Stage: Prim-5

Fig. 1

MZmid mutants lack notochords.

(A–C) Protein diagrams of FoxH1 alleles. (D–F) 24 hour post-fertilization (hpf) images of live wild-type and maternal-zygotic FoxH1 mutant embryos. (G–I) Dorsal zooms (2.5× relative magnification) of embryos in D–F at the level of the yolk extension. Red brackets mark the notochord; MZmid mutants lack this structure and exhibit midline-fused somites. (J–L) RNA in situ hybridization for ntl expression in 24 hpf wild-type and maternal-zygotic FoxH1 mutants.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
tbxta AB standard conditions Prim-5 notochord ISH
foxh1m768/m768 standard conditions Prim-5 notochord ISH
foxh1pr1/pr1 standard conditions Prim-5 Not Detected notochord ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
foxh1m768/m768 standard conditions Prim-5 notochord morphology, abnormal
Prim-5 whole organism anterior-posterior axis curved ventral, abnormal
foxh1pr1/pr1 standard conditions Prim-5 eye fused with eye, abnormal
Prim-5 notochord aplastic, abnormal
Prim-5 somite fused with somite, abnormal
Prim-5 whole organism anterior-posterior axis curved ventral, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS Genetics for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS Genet.