ZFIN ID: ZDB-GENE-980526-437
Gene Name: T, brachyury homolog a
Gene Symbol: ta
Sequence Ontology ID : SO:0000704

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Previous Names: brachyury, cb240 (1), id:ibd5074 (1), no tail a, ntl, ntla, T, wu:fc80a01 (1), ZF-NTL (1), ZF-T (1), zft

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 488 figures from 338 publications
Directly Submitted Expression Data: 7 figures (18 images) from Thisse et al., 2001 [cb240]
  1 figure (2 images) from Kudoh et al., 2001 [ibd5074]
Wild-type Stages, Structures: Blastula:128-cell (2.25h-2.5h) to Adult (90d-730d, breeding adult)
  anatomical structure, anterior axial hypoblast, axial chorda mesoderm, axial chorda mesoderm nucleus (all 56) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b160 Insertion Unknown Unknown G_RAYS
b195 Insertion Unknown Unknown SPONTANEOUS
  • Zebrafish International Resource Center (ZIRC) (order this)
  • b459 Unknown Unknown Unknown
    b487 Unknown Unknown Unknown
    kt338 Unknown Unknown Unknown
    kt501a Unknown Unknown Unknown
    kt633 Unknown Unknown Unknown
    m147 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m550 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13983 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • ta_unspecified Unspecified Unknown Unknown
    tb244e Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc41 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ts260 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • w181 Complex Unknown Unknown SPONTANEOUS
    Targeting reagents: CRISPR1-ta (1), MO1-ta (1), MO2-ta (1), MO3-ta (1), MO4-ta (1) (all 8) expand
    PHENOTYPE
    Data: 49 figures from 32 publications
    Observed in: adaxial cell, angioblast cell migration from lateral mesoderm to midline, calmodulin-dependent protein kinase activity, caudal fin (all 56) expand
    DISEASE ASSOCIATED WITH ta HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    {Neural tube defects, susceptibility to} 182940
    Sacral agenesis with vertebral anomalies 615709
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension involved in axis elongation (more)
    Cellular Component nuclear chromatin (more)
    Molecular Function DNA binding (more)
    GO Terms (all 35)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001699 (1)
  • InterPro:IPR002070 (1)
  • InterPro:IPR008967 (1)
  • InterPro:IPR018186 (1)
  • InterPro:IPR036960 (1)
  • PROSITE:PS01264 (1)
  • PROSITE:PS01283 (1)
  • PROSITE:PS50252 (1)
  • Pfam:PF00907 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ta-001 (1) 2211
    ncRNA ta-002 (1) 851
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-ta (1), Ab2-ta (1), AB3-ta (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ta
    Tg(-1ta:CFP), Tg(HSE:ntla-MYC,EGFP), Tg(ntla:GAL4-VP16), tg(ta:kaede), Tg(ta:LY-Tomato) (all 7) expand
    MARKER RELATIONSHIPS
    taContained in: [BAC] CH73-285B23 (1) (order this)
    taEncodes: [EST] cb240 (1), fc80a01 (1), ibd5074 (1) (order this)
    [cDNA] MGC:193897 (1) (order this), MGC:193903 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131162 (1) 2238bp
    Genomic GenBank:CU633985 (1) 108421bp
    Select Tool
    Polypeptide UniProtKB:Q07998 (1) 423aa
    Sequence Clusters UniGene:1468 (1)
    Sequence Information (all 24)
    OTHER ta GENE PAGES
  • Alliance (1)
  • Gene:30399 (1)
  • VEGA:OTTDARG00000032979 (1)
  • Ensembl(GRCz10):ENSDARG00000101576 (1)
  • ORTHOLOGY for ta (Chr: 19)
    CITATIONS (761)