ZFIN ID: ZDB-GENE-980526-437
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Gene Name: T-box transcription factor Ta
Gene Symbol: tbxta
Sequence Ontology ID : SO:0000704

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Previous Names: T, ta, ZF-T (1), zft, brachyury, cb240 (1), id:ibd5074 (1), no tail a, ntl, ntla, wu:fc80a01 (1), ZF-NTL (1)

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 499 figures from 345 publications
Directly Submitted Expression Data: 7 figures (18 images) from Thisse et al., 2001 [cb240]
  1 figure (2 images) from Kudoh et al., 2001 [ibd5074]
Wild-type Stages, Structures: Blastula:128-cell (2.25h-2.5h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b160 Insertion Unknown Unknown G_RAYS
b195 Insertion Unknown Unknown SPONTANEOUS
  • Zebrafish International Resource Center (ZIRC) (order this)
    • b459 Unknown Unknown Unknown
    b487 Unknown Unknown Unknown
    kt338 Unknown Unknown Unknown
    kt501a Unknown Unknown Unknown
    kt633 Unknown Unknown Unknown
    m147 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • m550 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa13983 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • tb244e Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
    • tbxta_unspecified Unspecified Unknown Unknown
    tc41 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
    • ts260 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
    • w181 Complex Unknown Unknown SPONTANEOUS
    Targeting reagents:
    PHENOTYPE
    Data: 50 figures from 33 publications
    Observed in:
    DISEASE ASSOCIATED WITH tbxta HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Sacral agenesis with vertebral anomalies 615709
    {Neural tube defects, susceptibility to} 182940
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension involved in axis elongation (more)
    Cellular Component nuclear chromatin (more)
    Molecular Function DNA binding (more)
    GO Terms (all 35)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001699 (1)
  • InterPro:IPR002070 (1)
  • InterPro:IPR008967 (1)
  • InterPro:IPR018186 (1)
  • InterPro:IPR036960 (1)
    		•
  • PROSITE:PS01264 (1)
  • PROSITE:PS01283 (1)
  • PROSITE:PS50252 (1)
    		•
  • Pfam:PF00907 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ta-001 (1) 2211
    Select Tool
    ncRNA ta-002 (1) 851
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tbxta
    MARKER RELATIONSHIPS
    tbxtaContained in: [BAC] CH73-285B23 (1) (order this)
    tbxtaEncodes: [EST] cb240 (1), fc80a01 (1), ibd5074 (1) (order this)
    [cDNA] MGC:193897 (1) (order this), MGC:193903 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131162 (1) 2238bp
    Select Tool
    Genomic GenBank:CU633985 (1) 108421bp
    Select Tool
    Polypeptide UniProtKB:Q07998 (1) 423aa
    Select Tool
    Sequence Clusters UniGene:1468 (1)
    Sequence Information (all 24)
    OTHER tbxta GENE PAGES
  • Alliance (1)
  • Gene:30399 (1)
  • VEGA:OTTDARG00000032979 (1)
  • Ensembl(GRCz10):ENSDARG00000101576 (1)
    • ORTHOLOGY for tbxta (Chr: 19)
    CITATIONS (785)