ZFIN

ZFIN ID: ZDB-GENE-040707-1

ZFIN ID: ZDB-GENE-040707-1

CITATIONS (49 total)

Gene Name:	iroquois homeobox 1a
Gene Symbol:	irx1a

England, S.J., Rusnock, A.K., Mujcic, A., Kowalchuk, A., de Jager, S., Hilinski, W.C., Juárez-Morales, J.L., Smith, M.E., Grieb, G., Banerjee, S., Lewis, K.E. (2023) Molecular analyses of zebrafish V0v spinal interneurons and identification of transcriptional regulators downstream of Evx1 and Evx2 in these cells. Neural Development. 18:88

Wesselman, H.M., Gatz, A.E., Pfaff, M.R., Arceri, L., Wingert, R.A. (2023) Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney. Cells. 12(4):

Halabi, R., Cechmanek, P.B., Hehr, C.L., McFarlane, S. (2022) Semaphorin3f as a cardiomyocyte derived regulator of heart chamber development. Cell communication and signaling : CCS. 20:126

Hehr, C.L., Halabi, R., McFarlane, S. (2022) Spatial regulation of amacrine cell genesis by Semaphorin 3f. Developmental Biology. 491:66-81

Weaver, N.E., Healy, A., Wingert, R.A. (2022) gldc Is Essential for Renal Progenitor Patterning during Kidney Development. Biomedicines. 10(12):

Farmer, D.T., Patel, P., Choi, R., Liu, C.Y., Crump, J.G. (2021) Comprehensive series of Irx cluster mutants reveals diverse roles in facial cartilage development. Development (Cambridge, England). 148(16)

Chambers, B.E., Gerlach, G.F., Clark, E.G., Chen, K.H., Levesque, A.E., Leshchiner, I., Goessling, W., Wingert, R.A. (2019) Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development (Cambridge, England). 146(13):

Jung, I.H., Jung, D.E., Chung, Y.Y., Kim, K.S., Park, S.W. (2019) Iroquois Homeobox 1 Acts as a True Tumor Suppressor in Multiple Organs by Regulating Cell Cycle Progression. Neoplasia (New York, N.Y.). 21:1003-1014

Falisse, E., Ducos, B., Stockwell, P.A., Morison, I.M., Chatterjee, A., Silvestre, F. (2018) DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan. Environmental pollution (Barking, Essex : 1987). 243:1867-1877

Morales, E.E., Handa, N., Drummond, B.E., Chambers, J.M., Marra, A.N., Addiego, A., Wingert, R.A. (2018) Homeogene emx1 is required for nephron distal segment development in zebrafish. Scientific Reports. 8:18038

Ott, E., Wendik, B., Srivastava, M., Pacho, F., Töchterle, S., Salvenmoser, W., Meyer, D. (2016) Pronephric tubule morphogenesis in zebrafish depends on Mnx mediated repression of irx1b within the intermediate mesoderm. Developmental Biology. 411(1):101-14

Singh, A.R., Sivadas, A., Sabharwal, A., Vellarikal, S.K., Jayarajan, R., Verma, A., Kapoor, S., Joshi, A., Scaria, V., Sivasubbu, S. (2016) Chamber Specific Gene Expression Landscape of the Zebrafish Heart. PLoS One. 11:e0147823

Winata, C.L., Kondrychyn, I., Kumar, V., Srinivasan, K.G., Orlov, Y., Ravishankar, A., Prabhakar, S., Stanton, L.W., Korzh, V., and Mathavan, S. (2013) Genome wide analysis reveals zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish. PLoS Genetics. 9(10):e1003852

Zhang, R., Han, P., Yang, H., Ouyang, K., Lee, D., Lin, Y.F., Ocorr, K., Kang, G., Chen, J., Stainier, D.Y., Yelon, D., and Chi, N.C. (2013) In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature. 498(7455):497-501

Paridaen, J.T., Janson, E., Utami, K.H., Pereboom, T.C., Essers, P.B., van Rooijen, C., Zivkovic, D., and Macinnes, A.W. (2011) The nucleolar GTP-binding proteins Gnl2 and nucleostemin are required for retinal neurogenesis in developing zebrafish. Developmental Biology. 355(2):286-301

Tena, J.J., Alonso, M.E., de la Calle-Mustienes, E., Splinter, E., de Laat, W., Manzanares, M., and Gómez-Skarmeta, J.L. (2011) An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation. Nature communications. 2:310

Choy, S.W., Cheng, C.W., Lee, S.T., Li, V.W., Hui, M.N., Hui, C.C., Liu, D., and Cheng, S.H. (2010) A cascade of irx1a and irx2a controls shh expression during retinogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(12):3204-3214

Li, S., Yin, M., Liu, S., Chen, Y., Yin, Y., Liu, T., and Zhou, J. (2010) Expression of ventral diencephalon-enriched genes in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(12):3368-3379

McDonald, L.A., Gerrelli, D., Fok, Y., Hurst, L.D., and Tickle, C. (2010) Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos. Journal of anatomy. 216(6):683-691

Diekmann, H., and Stuermer, C.A. (2009) Zebrafish neurolin-a and -b, orthologs of ALCAM, are involved in retinal ganglion cell differentiation and retinal axon pathfinding. The Journal of comparative neurology. 513(1):38-50

Paridaen, J.T., Danesin, C., Elas, A.T., van de Water, S., Houart, C., and Zivkovic, D. (2009) Apc1-Mediated Antagonism of Wnt/beta-Catenin Signaling Is Required for Retino-Tectal Pathfinding in the Zebrafish. Zebrafish. 6(1):41-47

Cheng, C.W., Yan, C.H., Choy, S.W., Hui, M.N., Hui, C.C., and Cheng, S.H. (2007) Zebrafish homologue irx1a is required for the differentiation of serotonergic neurons. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(9):2661-2667

Cheng, C.W., Yan, C.H., Hui, C.C., Strähle, U., and Cheng, S.H. (2006) The homeobox gene irx1a is required for the propagation of the neurogenic waves in the zebrafish retina. Mechanisms of Development. 123(3):252-263

Ju, Z., Wells, M.C., Martinez, A., Hazlewood, L., and Walter, R.B. (2005) An in silico mining for simple sequence repeats from expressed sequence tags of zebrafish, medaka, Fundulus, and Xiphophorus. In Silico Biology. 5(5-6):439-463

Lecaudey, V., Anselme, I., Dildrop, R., Ruther, U., and Schneider-Maunoury, S. (2005) Expression of the zebrafish Iroquois genes during early nervous system formation and patterning. The Journal of comparative neurology. 492(3):289-302

Dildrop, R., and Ruther, U. (2004) Organization of Iroquois genes in fish. Development genes and evolution. 214(6):267-276

Feijoo, C.G., Manzanares, M., De La Calle-Mustienes, E., Gómez-Skarmeta, J.L., and Allende, M.L. (2004) The Irx gene family in zebrafish: genomic structure, evolution and initial characterization of irx5b. Development genes and evolution. 214(6):277-284

Glavic, A., Maris Honoré, S., Gloria Feijóo, C., Bastidas, F., Allende, M.L., and Mayor, R. (2004) Role of BMP signaling and the homeoprotein iroquois in the specification of the cranial placodal field. Developmental Biology. 272(1):89-103

Joseph, E.M. (2004) Zebrafish IRX1b in the embryonic cardiac ventricle. Developmental Dynamics : an official publication of the American Association of Anatomists. 231(4):720-726

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Cheng, C.W., Hui, C.C., Strähle, U., and Cheng, S.H. (2001) Identification and expression of zebrafish Iroquois homeobox gene irx1. Development genes and evolution. 211(8-9):442-444

Additional Citations (18):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Computational Sequence to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.