Gene
irx1a
- ID
- ZDB-GENE-040707-1
- Name
- iroquois homeobox 1a
- Symbol
- irx1a Nomenclature History
- Previous Names
-
- ziro1a (1)
- zgc:109702
- zgc:136490
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Is predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cell development; neuron differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within central nervous system neuron differentiation; embryonic pectoral fin morphogenesis; and sensory organ development. Is expressed in several structures, including liver; nervous system; neural plate; pericardial region; and pleuroperitoneal region. Orthologous to human IRX1 (iroquois homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox, conserved site | Homeobox domain | Homeobox KN domain | Homeobox-like domain superfamily | Iroquois-class homeodomain protein |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4ILR3
|
419 | |||||
|
UniProtKB:B3DKL9
|
426 | |||||
|
UniProtKB:Q8JH33
|
419 | |||||
|
UniProtKB:Q90XQ7
|
426 | |||||
|
UniProtKB:Q568X8
|
148 |
Interactions and Pathways
No data available
Plasmids
No data available