| ZFIN ID: ZDB-PUB-011108-4 |
Identification and expression of zebrafish Iroquois homeobox gene irx1
Cheng, C.W., Hui, C.C., Strähle, U., and Cheng, S.H.
| Date: | 2001 |
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| Source: | Development genes and evolution 211(8-9): 442-444 (Journal) |
| Registered Authors: | Cheng, Shuk Han, Strähle, Uwe |
| Keywords: | tectum; tegmentum; trigeminal ganglia; rhombomere; homeobox gene |
| MeSH Terms: |
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| PubMed: | 11685579 Full text @ Dev. Genes Evol. |
Citation
Cheng, C.W., Hui, C.C., Strähle, U., and Cheng, S.H. (2001) Identification and expression of zebrafish Iroquois homeobox gene irx1. Development genes and evolution. 211(8-9):442-444.
ABSTRACT
Iroquois homeoproteins are prepatterning factors that positively regulate proneural genes and control neurogenesis. We have identified a zebrafish Iroquois gene, irx1, which is highly homologous to Xenopus Xiro1, Gallus c-Irx1 and mouse Irx1. Expression of irx1 was initially detected at the bud stage. By 16 h post-fertilization (hpf), irx1 expression was exclusively limited to the prospective midbrain and hindbrain. By 24 hpf, irx1 expression was clearly detected in the acousticovestibual ganglia, tectum, tegmentum, cerebellum and rhombomere 1 but not in rhombomere 2 or mid-hindbrain boundary.
ADDITIONAL INFORMATION
- Genes / Markers (1)
- Orthology (2)