ZFIN

ZFIN ID: ZDB-GENE-040426-2286

ZFIN ID: ZDB-GENE-040426-2286

CITATIONS (68 total)

Gene Name:	RAD51 recombinase
Gene Symbol:	rad51

Bhagat, J., Zang, L., Kaneco, S., Nishimura, N., Shimada, Y. (2022) Combined exposure to nanoplastics and metal oxide nanoparticles inhibits efflux pumps and causes oxidative stress in zebrafish embryos. The Science of the total environment. 835:155436

Chatterjee, A., Maity, S., Banerjee, S., Dutta, S., Adhikari, M., Guchhait, R., Biswas, C., De, S., Pramanick, K. (2022) Toxicological impacts of nanopolystyrene on zebrafish oocyte with insight into the mechanism of action: An expression-based analysis. The Science of the total environment. 830:154796

Li, L., Chen, M., Liu, W., Tai, P., Liu, X., Liu, J.X. (2022) Zebrafish cox17 modulates primitive erythropoiesis via regulation of mitochondrial metabolism to facilitate hypoxia tolerance. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36:e22596

Rozenblat, R., Tovin, A., Zada, D., Lebenthal-Loinger, I., Lerer-Goldshtein, T., Appelbaum, L. (2022) Genetic and Neurological Deficiencies in the Visual System of mct8 Mutant Zebrafish. International Journal of Molecular Sciences. 23(5):

Dai, X., Cheng, X., Huang, J., Gao, Y., Wang, D., Feng, Z., Zhai, G., Lou, Q., He, J., Wang, Z., Yin, Z. (2021) Rbm46, a novel germ cell specific factor, modulates meiotic progression and spermatogenesis. Biology of reproduction. 104(5):1139-1153

Eid, J.I., Al-Tuwaijri, M.M., Mohanty, S., Das, B. (2021) Chaga mushroom (Inonotus obliquus) polysaccharides exhibit genoprotective effects in UVB-exposed embryonic zebrafish (Danio rerio) through coordinated expression of DNA repair genes. Heliyon. 7:e06003

Falfushynska, H., Horyn, O., Osypenko, I., Rzymski, P., Wejnerowski, Ł., Dziuba, M.K., Sokolova, I.M. (2021) Multibiomarker-based assessment of toxicity of central European strains of filamentous cyanobacteria Aphanizomenon gracile and Raphidiopsis raciborskii to zebrafish Danio rerio. Water research. 194:116923

Shin, U., Nakhro, K., Oh, C.K., Carrington, B., Song, H., Varshney, G.K., Kim, Y., Song, H., Jeon, S., Robbins, G., Kim, S., Yoon, S., Choi, Y.J., Kim, Y.J., Burgess, S., Kang, S., Sood, R., Lee, Y., Myung, K. (2021) Large-scale generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes. DNA repair. 107:103173

Yang, L., Webb, S.E., Jin, N., Lee, H.M., Chan, T.F., Xu, G., Chan, J.C.N., Miller, A.L., Ma, R.C.W. (2021) Investigating the role of dachshund b in the development of the pancreatic islet in zebrafish. Journal of diabetes investigation. 12(5):710-727

Hu, J., Liu, J., Li, J., Lv, X., Yu, L., Wu, K., Yang, Y. (2020) Metal contamination, bioaccumulation, ROS generation, and epigenotoxicity influences on zebrafish exposed to river water polluted by mining activities. Journal of hazardous materials. 405:124150

Wahyuni, E.A., Lin, H.D., Lu, C.W., Kao, C.M., Chen, S.C. (2020) The cytotoxicity and genotoxicity of single and combined fenthion and terbufos treatments in human liver cells and zebrafish embryos. The Science of the total environment. 758:143597

Xie, H., Kang, Y., Wang, S., Zheng, P., Chen, Z., Roy, S., Zhao, C. (2020) E2f5 is a versatile transcriptional activator required for spermatogenesis and multiciliated cell differentiation in zebrafish. PLoS Genetics. 16:e1008655

Bereketoglu, C., Pradhan, A. (2019) Comparative transcriptional analysis of methylparaben and propylparaben in zebrafish. The Science of the total environment. 671:129-139

Boran, H., Terzi, S. (2019) Bis(2-ethylhexyl) phthalate induces DNA strand breaks and gene expression alterations in larval zebrafish Danio rerio. Toxicology and industrial health. 35:520-529

Sun, H., Chen, M., Wang, Z., Zhao, G., Liu, J.X. (2019) Transcriptional profiles and copper stress responses in zebrafish cox17 mutants. Environmental pollution (Barking, Essex : 1987). 256:113364

Arcanjo, C., Armant, O., Floriani, M., Cavalie, I., Camilleri, V., Simon, O., Orjollet, D., Adam-Guillermin, C., Gagnaire, B. (2018) Tritiated water exposure disrupts myofibril structure and induces mis-regulation of eye opacity and DNA repair genes in zebrafish early life stages. Aquatic toxicology (Amsterdam, Netherlands). 200:114-126

Komoike, Y., Matsuoka, M. (2018) In vitro and in vivo studies of oxidative stress responses against acrylamide toxicity in zebrafish. Journal of hazardous materials. 365:430-439

Liu, H., Wang, X., Wu, Y., Hou, J., Zhang, S., Zhou, N., Wang, X. (2018) Toxicity responses of different organs of zebrafish (Danio rerio) to silver nanoparticles with different particle sizes and surface coatings. Environmental pollution (Barking, Essex : 1987). 246:414-422

Boran, H., Terzi, S. (2017) Stress-Induced Transcriptional Changes and DNA Damage Associated with Bis(2-ethylhexyl) Adipate Exposure in Zebrafish (Danio rerio) Larvae. Bulletin of environmental contamination and toxicology. 99(3):308-314

Boran, H., Şaffak, S. (2017) Comparison of Dissolved Nickel and Nickel Nanoparticles Toxicity in Larval Zebrafish in Terms of Gene Expression and DNA Damage. Archives of environmental contamination and toxicology. 74(1):193-202

Botthof, J.G., Bielczyk-Maczyńska, E., Ferreira, L., Cvejic, A. (2017) Loss of the homologous recombination gene rad51 leads to Fanconi anemia-like symptoms in zebrafish.. Proceedings of the National Academy of Sciences of the United States of America. 114(22):E4452-E4461

Gombeau, K., Bourdineaud, J.P., Ravanat, J.L., Armant, O., Camilleri, V., Cavalie, I., Floriani, M., Adam-Guillermin, C. (2017) Epigenetic, histopathological and transcriptomic effects following exposure to depleted uranium in adult zebrafish and their progeny. Aquatic toxicology (Amsterdam, Netherlands). 184:14-25

Pradhan, A., Ivarsson, P., Ragnvaldsson, D., Berg, H., Jass, J., Olsson, P.E. (2017) Transcriptional responses of zebrafish to complex metal mixtures in laboratory studies overestimates the responses observed with environmental water. The Science of the total environment. 584-585:1138-1146

Singh, R., Khatri, P., Srivastava, N., Jain, S., Bramchari, V., Mukhopadhyay, A., Mazumder, S. (2017) Fluoride exposure abates pro-inflammatory response and induces in vivo apoptosis rendering zebrafish (Danio rerio) susceptible to bacterial infections. Fish & shellfish immunology. 63:314-321

Dedeh, A., Ciutat, A., Treguer-Delapierre, M., Bourdineaud, J.P. (2015) Impact of gold nanoparticles on zebrafish exposed to a spiked sediment. Nanotoxicology. 9:71-80

Gentès, S., Maury-Brachet, R., Feng, C., Pedrero, Z., Tessier, E., Legeay, A., Mesmer-Dudons, N., Baudrimont, M., Maurice, L., Amouroux, D., Gonzalez, P. (2015) Specific effects of dietary methylmercury and inorganic mercury in zebrafish (Danio rerio) determined by genetic, histological and metallothionein responses. Environmental science & technology. 49(24):14560-9

Gong, L., Gong, H., Pan, X., Chang, C., Ou, Z., Ye, S., Yin, L., Yang, L., Tao, T., Zhang, Z., Liu, C., Lane, D.P., Peng, J., Chen, J. (2015) p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage. Cell Research. 25(3):351-69

Šrut, M., Bourdineaud, J.P., Štambuk, A., Klobučar, G.I. (2015) Genomic and gene expression responses to genotoxic stress in PAC2 zebrafish embryonic cell line. Journal of applied toxicology : JAT. 35(11):1381-9

Chen, Y.Y., Zhu, J.Y., Chan, K.M. (2014) Effects of cadmium on cell proliferation, apoptosis, and proto-oncogene expression in zebrafish liver cells. Aquatic toxicology (Amsterdam, Netherlands). 157C:196-206

Ladhar, C., Geffroy, B., Cambier, S., Treguer-Delapierre, M., Durand, E., Brèthes, D., and Bourdineaud, J.P. (2014) Impact of dietary cadmium sulphide nanoparticles on Danio rerio zebrafish at very low contamination pressure. Nanotoxicology. 8:676-85

Reinardy, H.C., Dharamshi, J., Jha, A.N., and Henry, T.B. (2013) Changes in expression profiles of genes associated with DNA repair following induction of DNA damage in larval zebrafish Danio rerio. Mutagenesis. 28(5):601-608

Reinardy, H.C., Syrett, J.R., Jeffree, R.A., Henry, T.B., and Jha, A.N. (2013) Cobalt-induced genotoxicity in male zebrafish (Danio rerio), with implications for reproduction and expression of DNA repair genes. Aquatic toxicology (Amsterdam, Netherlands). 126C:224-230

Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735

Cui, X., Zhang, J., Du, R., Wang, L., Archacki, S., Zhang, Y., Yuan, M., Ke, T., Li, H., Li, D., Li, C., Li, D.W., Tang, Z., Yin, Z., and Liu, M. (2012) HSF4 is involved in DNA damage repair through regulation of Rad51. Biochimica et biophysica acta. Molecular basis of disease. 1822(8):1308-1315

Liu, J., Gong, L., Chang, C., Liu, C., Peng, J., and Chen, J. (2012) Development of novel visual-plus quantitative analysis systems for studying DNA double-strand break repairs in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 39(9):489-502

Orieux, N., Cambier, S., Gonzalez, P., Morin, B., Adam, C., Garnier-Laplace, J., and Bourdineaud, J.P. (2011) Genotoxic damages in zebrafish submitted to a polymetallic gradient displayed by the Lot River (France). Ecotoxicology and environmental safety. 74(4):974-983

Sissener, N.H., Johannessen, L.E., Hevrøy, E.M., Wiik-Nielsen, C.R., Berdal, K.G., Nordgreen, A., and Hemre, G.I. (2010) Zebrafish ( Danio rerio) as a model for investigating the safety of GM feed ingredients (soya and maize); performance, stress response and uptake of dietary DNA sequences. The British journal of nutrition. 103(1):3-15

Anelli, V., Santoriello, C., Distel, M., Köster, R.W., Ciccarelli, F.D., and Mione, M. (2009) Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation. Zebrafish. 6(4):417-424

Lerebours, A., Gonzalez, P., Adam, C., Camilleri, V., Bourdineaud, J.P., and Garnier-Laplace, J. (2009) Comparative Analysis Of Gene Expression In Brain, Liver, Skeletal Muscles And Gills Of The Zebrafish (Danio rerio) Exposed To Environmentally Relevant Waterborne Uranium Concentrations. Environmental toxicology and chemistry. 28(6):1271-1278

Sandrini, J.Z., Bianchini, A., Trindade, G.S., Nery, L.E., and Marins, L.F. (2009) Reactive oxygen species generation and expression of DNA repair-related genes after copper exposure in zebrafish (Danio rerio) ZFL cells. Aquatic toxicology (Amsterdam, Netherlands). 95(4):285-291

Sandrini, J.Z., Trindade, G.S., Nery, L.E., and Marins, L.F. (2009) Time-course Expression of DNA Repair-related Genes in Hepatocytes of Zebrafish (Danio rerio) After UV-B Exposure. Photochemistry and photobiology. 85(1):220-226

Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433

Gonzalez, P., Baudrimont, M., Boudou, A., and Bourdineaud, J.P. (2006) Comparative Effects of Direct Cadmium Contamination on Gene Expression in Gills, Liver, Skeletal Muscles and Brain of the Zebrafish (Danio rerio). Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 19(3):225-235

Gonzalez, P., Dominique, Y., Massabuau, J.C., Boudou, A., and Bourdineaud, J.P. (2005) Comparative effects of dietary methylmercury on gene expression in liver, skeletal muscle, and brain of the zebrafish (Danio rerio). Environmental science & technology. 39(11):3972-3980

Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (22):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.

Burgess, S., and Lin, S. (2011) Viral Insertion Mutants. ZFIN Direct Data Submission.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.