ZFIN

ZFIN ID: ZDB-GENE-030411-5

ZFIN ID: ZDB-GENE-030411-5

CITATIONS (78 total)

Gene Name:	keratin 8
Gene Symbol:	krt8

Ligunas, G.D., Paniagua, G., LaBelle, J., Ramos-Martinez, A., Shen, K., Gerlt, E.H., Aguilar, K., Nguyen, N., Materna, S.C., Woo, S. (2024) Tissue-specific and endogenous protein labeling with split fluorescent proteins. Developmental Biology. 514:109-116

Williams, A.L., Bohnsack, B.L. (2024) Keratin 8/18a.1 Expression Influences Embryonic Neural Crest Cell Dynamics and Contributes to Postnatal Corneal Regeneration in Zebrafish. Cells. 13(17):

Baniel, A., Ziv, L., Ben-Moshe, Z., Sarig, O., Mohamad, J., Peled, A., Rechavi, G., Gothilf, Y., Sprecher, E. (2022) Cutaneous and Developmental Effects of CARD14 Overexpression in Zebrafish. Biomedicines. 10(12):

Charlie-Silva, I., Feitosa, N.M., Pontes, L.G., Fernandes, B.H., Nóbrega, R.H., Gomes, J.M.M., Prata, M.N.L., Ferraris, F.K., Melo, D.C., Conde, G., Rodrigues, L.F., Aracati, M.F., Corrêa-Junior, J.D., Manrique, W.G., Superio, J., Garcez, A.S., Conceição, K., Yoshimura, T.M., Núñez, S.C., Eto, S.F., Fernandes, D.C., Freitas, A.Z., Ribeiro, M.S., Nedoluzhko, A., Lopes-Ferreira, M., Borra, R.C., Barcellos, L.J.G., Perez, A.C., Malafaia, G., Cunha, T.M., Belo, M.A.A., Galindo-Villegas, J. (2022) Plasma proteome responses in zebrafish following λ-carrageenan-Induced inflammation are mediated by PMN leukocytes and correlate highly with their human counterparts. Frontiers in immunology. 13:1019201

Ho, M., Thompson, B., Fisk, J.N., Nebert, D.W., Bruford, E.A., Vasiliou, V., Bunick, C.G. (2022) Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders. Human genomics. 16:1

Horzmann, K.A., Lin, L.F., Taslakjian, B., Yuan, C., Freeman, J.L. (2022) Anxiety-related behavior and associated brain transcriptome and epigenome alterations in adult female zebrafish exposed to atrazine during embryogenesis. Chemosphere. 308(Pt 3):136431

Miyamoto, K., Kawakami, K., Tamura, K., Abe, G. (2022) Developmental independence of median fins from the larval fin fold revises their evolutionary origin. Scientific Reports. 12:7521

Buono, L., Corbacho, J., Naranjo, S., Almuedo-Castillo, M., Moreno-Marmol, T., de la Cerda, B., Sanbria-Reinoso, E., Polvillo, R., Díaz-Corrales, F.J., Bogdanovic, O., Bovolenta, P., Martínez-Morales, J.R. (2021) Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish. Nature communications. 12:3866

Pradhan, S.J., Reddy, P.C., Smutny, M., Sharma, A., Sako, K., Oak, M.S., Shah, R., Pal, M., Deshpande, O., Dsilva, G., Tang, Y., Mishra, R., Deshpande, G., Giraldez, A.J., Sonawane, M., Heisenberg, C.P., Galande, S. (2021) Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. Nature communications. 12:6094

Iwanami, N., Takeshita, K., Lawir, D.F., Suetake, I., Tajima, S., Sikora, K., Trancoso, I., ÓMeara, C., Siamishi, I., Takahama, Y., Furutani-Seiki, M., Kondoh, H., Yonezawa, Y., Schorpp, M., Boehm, T. (2020) Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1. iScience. 23:101260

Paudel, Y.N., Kumari, Y., Abidin, S.A.Z., Othman, I., Shaikh, M.F. (2020) Pilocarpine Induced Behavioral and Biochemical Alterations in Chronic Seizure-Like Condition in Adult Zebrafish. International Journal of Molecular Sciences. 21(7):

Zhang, X., Zhou, Q., Li, X., Zou, W., Hu, X. (2020) Integrating omics and traditional analyses to profile the synergistic toxicity of graphene oxide and triphenyl phosphate. Environmental pollution (Barking, Essex : 1987). 263:114473

Cokus, S.J., De La Torre, M., Medina, E.F., Rasmussen, J.P., Ramirez-Gutierrez, J., Sagasti, A., Wang, F. (2019) Tissue-Specific Transcriptomes Reveal Gene Expression Trajectories in Two Maturing Skin Epithelial Layers in Zebrafish Embryos. G3 (Bethesda). 9(10):3439-3452

Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613

Goto, H., Kimmey, S.C., Row, R.H., Matus, D.Q., Martin, B.L. (2017) FGF and canonical Wnt signaling cooperate to induce paraxial mesoderm from tailbud neuromesodermal progenitors through regulation of a two-step EMT. Development (Cambridge, England). 144(8):1412-1424

Seleit, A., Krämer, I., Riebesehl, B.F., Ambrosio, E.M., Stolper, J.S., Lischik, C.Q., Dross, N., Centanin, L. (2017) Neural stem cells induce the formation of their physical niche during organogenesis. eLIFE. 6

Shen, H., Shin, E.M., Lee, S., Mathavan, S., Koh, H., Osato, M., Choi, H., Tergaonkar, V., Korzh, V. (2017) Ikk2 regulates cytokinesis during vertebrate development. Scientific Reports. 7:8094

Travin, D., Popov, I., Guler, A.T., Medvedev, D., van der Plas-Duivesteijn, S., Varela, M., Kolder, I.C.R.M., Meijer, A.H., Spaink, H.P., Palmblad, M. (2017) COMICS: Cartoon Visualization of Omics Data in Spatial Context using Anatomical Ontologies. Journal of Proteome Research. 17(1):739-744

Chen, W.C., Wang, Z., Missinato, M.A., Park, D.W., Long, D.W., Liu, H.J., Zeng, X., Yates, N.A., Kim, K., Wang, Y. (2016) Decellularized zebrafish cardiac extracellular matrix induces mammalian heart regeneration. Science advances. 2:e1600844

Li, C., Tan, X.F., Lim, T.K., Lin, Q., Gong, Z. (2016) Comprehensive and quantitative proteomic analyses of zebrafish plasma reveals conserved protein profiles between genders and between zebrafish and human. Scientific Reports. 6:24329

Dzafic, E., Strzyz, P.J., Wilsch-Bräuninger, M., Norden, C. (2015) Centriole Amplification in Zebrafish Affects Proliferation and Survival but Not Differentiation of Neural Progenitor Cells. Cell Reports. 13(1):168-82

Chen, C.H., Lin, D.S., Cheng, C.W., Lin, C.J., Lo, Y.K., Yen, C.C., Lee, A.Y., Hsiao, C.D. (2014) Cdc6 cooperates with c-Myc to promote genome instability and EMT in zebrafish. Oncotarget. 5(15):6300-11

Fischer, B., Metzger, M., Richardson, R., Knyphausen, P., Ramezani, T., Franzen, R., Schmelzer, E., Bloch, W., Carney, T.J., and Hammerschmidt, M. (2014) p53 and TAp63 promote keratinocyte proliferation and differentiation in breeding tubercles of the zebrafish. PLoS Genetics. 10(1):e1004048

Podok, P., Wang, H., Xu, L., Xu, D., Lu, L. (2014) Characterization of myeloid-specific peroxidase, keratin 8, and dual specificity phosphatase 1 as innate immune genes involved in theresistance of crucian carp (Carassius auratus gibelio) to Cyprinid herpesvirus 2 infection. Fish & shellfish immunology. 41(2):531-40

Simões, M.G., Bensimon-Brito, A., Fonseca, M., Farinho, A., Valério, F., Sousa, S., Kumar, A., Jacinto, A. (2014) Denervation impairs regeneration of amputated zebrafish fins. BMC Developmental Biology. 14:780

Graham, D.M., Huang, L., Robinson, K.R., and Messerli, M.A. (2013) Epidermal keratinocyte polarity and motility require Ca²⁺ influx through TRPV1. Journal of Cell Science. 126(Pt 20):4602-13

Huang, T.C., and Chen, J.Y. (2013) Proteomic and functional analysis of zebrafish after administration of antimicrobial peptide epinecidin-1. Fish & shellfish immunology. 34(2):593-598

Tong, X., Xia, Z., Zu, Y., Telfer, H., Hu, J., Yu, J., Liu, H., Zhang, Q., Sodmergen, D., Lin, S., and Zhang, B. (2013) Ngs (notochord granular surface) encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish. The Journal of biological chemistry. 288(4):2711-2720

Gündel, U., Kalkhof, S., Zitzkat, D., von Bergen, M., Altenburger, R., and Küster, E. (2012) Concentration-response concept in ecotoxicoproteomics: Effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome. Ecotoxicology and environmental safety. 76(2):11-22

Lambaerts, K., Van Dyck, S., Mortier, E., Ivarssonm, Y., Degeest, G., Luyten, A., Vermeiren, E., Peers, B., David, G., and Zimmermann, P. (2012) Syntenin, a syndecan adaptor and an Arf6 phosphatidylinositol 4,5-bisphosphate effector, is essential for epiboly and gastrulation cell movements in zebrafish. Journal of Cell Science. 125(5):1129-1140

Ling, X.P., Lu, Y.H., and Huang, H.Q. (2012) Differential protein profile in zebrafish (Danio rerio) brain under the joint exposure of methyl parathion and cadmium. Environmental science and pollution research international. 19(9):3925-3941

Lam, S.H., Hlaing, M.M., Zhang, X., Yan, C., Duan, Z., Zhu, L., Ung, C.Y., Mathavan, S., Ong, C.N., and Gong, Z. (2011) Toxicogenomic and phenotypic analyses of bisphenol-a early-life exposure toxicity in zebrafish. PLoS One. 6(12):e28273

Li, X., Nie, F., Yin, Z., and He, J. (2011) Enhanced hyperplasia in muscles of transgenic zebrafish expressing Follistatin1. Science China. Life sciences. 54(2):159-165

Schwend, T., Loucks, E.J., Snyder, D., and Ahlgren, S.C. (2011) Requirement of Npc1 and availability of cholesterol for early embryonic cell movements in Zebrafish. Journal of Lipid Research. 52(7):1328-44

Fukazawa, C., Santiago, C., Park, K.M., Deery, W.J., Canny, S.G., Holterhoff, C.K., and Wagner, D.S. (2010) poky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis. Developmental Biology. 346(2):272-283

Shi, G., Sohn, K.C., Choi, T.Y., Choi, D.K., Lee, S.S., Ou, B.S., Kim, S., Lee, Y.H., Yoon, T.J., Kim, S.J., Lee, Y., Seo, Y.J., Lee, J.H., and Kim, C.D. (2010) Expression of paired-like homeodomain transcription factor 2c (PITX2c) in epidermal keratinocytes. Experimental cell research. 316(19):3263-3271

Tsujimura, T., Hosoya, T., and Kawamura, S. (2010) A single enhancer regulating the differential expression of duplicated red-sensitive opsin genes in zebrafish. PLoS Genetics. 6(12):e1001245

Quek, S.I., and Chan, W.K. (2009) Transcriptional activation of zebrafish cyp11a1 promoter is dependent on the nuclear receptor Ff1b. Journal of molecular endocrinology. 43(3):121-130

Sabel, J.L., d'Alençon, C., O'Brien, E.K., Otterloo, E.V., Lutz, K., Cuykendall, T.N., Schutte, B.C., Houston, D.W., and Cornell, R.A. (2009) Maternal Interferon Regulatory Factor 6 is required for the differentiation of primary superficial epithelia in Danio and Xenopus embryos. Developmental Biology. 325(1):249-262

Emelyanov, A., and Parinov, S. (2008) Mifepristone-inducible LexPR system to drive and control gene expression in transgenic zebrafish. Developmental Biology. 320(1):113-121

Leung, Y.F., Ma, P., and Dowling, J.E. (2007) Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo. Investigative ophthalmology & visual science. 48(2):881-890

Pei, W., Noushmehr, H., Costa, J., Ouspenskaia, M.V., Elkahloun, A.G., and Feldman, B. (2007) An early requirement for maternal FoxH1 during zebrafish gastrulation. Developmental Biology. 310(1):10-22

Padhi, B.K., Akimenko, M.A., and Ekker, M. (2006) Independent expansion of the keratin gene family in teleostean fish and mammals: An insight from phylogenetic analysis and radiation hybrid mapping of keratin genes in zebrafish. Gene. 368:37-45

Garcia, D.M., Bauer, H., Dietz, T., Schubert, T., Markl, J., and Schaffeld, M. (2005) Identification of keratins and analysis of their expression in carp and goldfish: comparison with the zebrafish and trout keratin catalog. Cell and tissue research. 322(2):245-256

Vihtelic, T.S., Fadool, J.M., Gao, J., Thornton, K.A., Hyde, D.R., and Wistow, G. (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Molecular Vision. 11:1083-1100

Padhi, B.K., Joly, L., Tellis, P., Smith, A., Nanjappa, P., Chevrette, M., Ekker, M., and Akimenko, M.A. (2004) Screen for genes differentially expressed during regeneration of the zebrafish caudal fin. Developmental Dynamics : an official publication of the American Association of Anatomists. 231(3):527-541

Song, H.D., Sun, X.J., Deng, M., Zhang, G.W., Zhou, Y., Wu, X.Y., Sheng, Y., Chen, Y., Ruan, Z., Jiang, C.L., Fan, H.Y., Zon, L.I., Kanki, J.P., Liu, T.X., Look, A.T., and Chen, Z. (2004) Hematopoietic gene expression profile in zebrafish kidney marrow. Proceedings of the National Academy of Sciences of the United States of America. 101(46):16240-16245

Schaffeld, M., Knappe, M., Hunzinger, C., and Markl, J. (2003) cDNA sequences of the authentic keratins 8 and 18 in zebrafish. Differentiation; research in biological diversity. 71(1):73-82

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Martorana, M.L., Tawk, M., Lapointe, T., Barre, N., Imboden, M., Joulie, C., Géraudie, J., and Vriz, S. (2001) Zebrafish keratin 8 is expressed at high levels in the epidermis of regenerating caudal fin. The International journal of developmental biology. 45(2):449-452

Imboden, M., Goblet, C., Korn, H., and Vriz, S. (1997) Cytokeratin 8 is a suitable epidermal marker during zebrafish development. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 320:689-700

Additional Citations (27):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Busch-Nentwich, E., Kettleborough, R., Harvey, S., Collins, J., Ding, M., Dooley, C., Fenyes, F., Gibbons, R., Herd, C., Mehroke, S., Scahill, C., Sealy, I., Wali, N., White, R., and Stemple, D.L. (2012) Sanger Institute Zebrafish Mutation Project mutant, phenotype and image data submission. ZFIN Direct Data Submission.

UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. Manually curated data.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

GOA curators, UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. Manually curated data.

GOA, HGNC, AgBase and UniProtKB curators (2007) Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. ZFIN Direct Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of FPC Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

ZFIN Staff (2003) Computational Sequence to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

Thisse, B., Pflumio, S., Fürthauer, M., Loppin, B., Heyer, V., Degrave, A., Woehl, R., Lux, A., Steffan, T., Charbonnier, X.Q. and Thisse, C. (2001) Expression of the zebrafish genome during embryogenesis (NIH R01 RR15402). ZFIN Direct Data Submission.