ZFIN

ZFIN ID: ZDB-GENE-001201-4

ZFIN ID: ZDB-GENE-001201-4

CITATIONS (67 total)

Gene Name:	vitellogenin 5
Gene Symbol:	vtg5

Uju, C., Unniappan, S. (2025) Brain Derived Neurotrophic Factor Promotes Oocyte Maturation Through the TrkB-MAPk-PI3K Pathway in Zebrafish. Molecular and Cellular Endocrinology. :112703

Liu, Z., Zhang, N., Wang, C., Shi, L., Hu, Y., Wang, Y., Li, J. (2024) Lrp13a and Lrp13b serve as vitellogenin receptors in the ovary of zebrafish†. Biology of reproduction. 111(1):123-134

Uju, C., Karimzadeh, K., Unniappan, S. (2024) Brain Derived Neurotrophic Factor Stimulates Hypothalamic and Gonadal Reproductive Hormones and Oocyte Maturation in Zebrafish. Reproduction (Cambridge, England). 169(1):

Zhu, B., Zhang, Z., Pardeshi, L., Chen, Y., Ge, W. (2024) Role of Y box-binding protein 1 (Ybx1) in zebrafish folliculogenesis: Promoting follicle cell proliferation via suppression of p21 (cdkn1a). Development (Cambridge, England). 151(21):

Sun, S.X., Liu, Y.C., Limbu, S.M., Li, D.L., Chen, L.Q., Zhang, M.L., Yin, Z., Du, Z.Y. (2023) Vitellogenin 1 is essential for fish reproduction by transporting DHA-containing phosphatidylcholine from liver to ovary. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1868(4):159289

Yilmaz, O., Com, E., Pineau, C., Bobe, J. (2023) Genomic disturbance of vitellogenin 2 (vtg2) leads to vitellin membrane deficiencies and significant mortalities at early stages of embryonic development in zebrafish (Danio rerio). Scientific Reports. 13:18795

Zhai, Y., Zhang, X., Zhao, C., Geng, R., Wu, K., Yuan, M., Ai, N., Ge, W. (2023) Rescue of bmp15 deficiency in zebrafish by mutation of inha reveals mechanisms of BMP15 regulation of folliculogenesis. PLoS Genetics. 19:e1010954

Song, Y., Chen, W., Zhu, B., Ge, W. (2022) Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish Ovary. Frontiers in cell and developmental biology. 9:750888

Liu, X., Xie, X., Liu, H. (2021) Effects of Diethylstilbestrol on Zebrafish Gonad Development and Endocrine Disruption Mechanism. Biomolecules. 11(7):

Spreafico, M., Cafora, M., Bragato, C., Capitanio, D., Marasca, F., Bodega, B., De Palma, C., Mora, M., Gelfi, C., Marozzi, A., Pistocchi, A. (2021) Targeting HDAC8 to ameliorate skeletal muscle differentiation in Duchenne muscular dystrophy. Pharmacological research. 170:105750

Yilmaz, O., Patinote, A., Com, E., Pineau, C., Bobe, J. (2021) Knock out of specific maternal vitellogenins in zebrafish (Danio rerio) evokes vital changes in egg proteomic profiles that resemble the phenotype of poor quality eggs. BMC Genomics. 22:308

Maradonna, F., Gioacchini, G., Notarstefano, V., Fontana, C.M., Citton, F., Dalla Valle, L., Giorgini, E., Carnevali, O. (2020) Knockout of the Glucocorticoid Receptor Impairs Reproduction in Female Zebrafish. International Journal of Molecular Sciences. 21(23):

Rajeswari, J.J., Unniappan, S. (2020) Phoenixin-20 Stimulates mRNAs Encoding Hypothalamo-Pituitary-Gonadal Hormones, is Pro-Vitellogenic, and Promotes Oocyte Maturation in Zebrafish. Scientific Reports. 10:6264

Xu, S., Xie, F., Tian, L., Fallah, S., Babaei, F., Manno, S.H., Manno Iii, F.A.M., Zhu, L., Wong, K.F., Liang, Y., Ramalingam, R., Sun, L., Wang, X., Plumb, R., Gethings, L., Lam, Y.W., Cheng, S.H. (2020) Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish. The Journal of endocrinology. 245(1):39-51

Jiao, F., Qiao, K., Jiang, Y., Li, S., Zhao, J., Gui, W. (2019) Integrated thyroid endocrine disrupting effect on zebrafish (Danio rario) larvae via simultaneously repressing type II iodothyronine deiodinase and activating thyroid receptor-mediated signaling following waterborne exposure to trace azocyclotin. Environmental pollution (Barking, Essex : 1987). 255:113328

Xie, X., Jin, Y., Ma, Z., Tang, S., Peng, H., Giesy, J.P., Liu, H. (2019) Underlying mechanisms of reproductive toxicity caused by multigenerational exposure of 2, bromo-4, 6-dinitroaniline (BDNA) to Zebrafish (Danio rerio) at environmental relevant levels. Aquatic toxicology (Amsterdam, Netherlands). 216:105285

Yilmaz, O., Patinote, A., Nguyen, T., Com, E., Pineau, C., Bobe, J. (2019) Genome editing reveals reproductive and developmental dependencies on specific types of vitellogenin in zebrafish (Danio rerio). Molecular reproduction and development. 86(9):1168-1188

Adam, A.C., Skjærven, K.H., Whatmore, P., Moren, M., Lie, K.K. (2018) Parental high dietary arachidonic acid levels modulated the hepatic transcriptome of adult zebrafish (Danio rerio) progeny. PLoS One. 13:e0201278

Chen, Y., Tang, H., Wang, L., He, J., Guo, Y., Liu, Y., Liu, X., Lin, H. (2018) Fertility Enhancement but Premature Ovarian Failure in esr1-Deficient Female Zebrafish.. Frontiers in endocrinology. 9:567

Hou, J., Liu, H., Wang, L., Duan, L., Li, S., Wang, X. (2018) Molecular Toxicity of Metal Oxide Nanoparticles in Danio rerio. Environmental science & technology. 52(14):7996-8004

Parolini, M., Bini, L., Magni, S., Rizzo, A., Ghilardi, A., Landi, C., Armini, A., Del Giacco, L., Binelli, A. (2018) Exposure to cocaine and its main metabolites altered the protein profile of zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 232:603-614

Yilmaz, O., Patinote, A., Nguyen, T., Bobe, J. (2018) Multiple vitellogenins in zebrafish (Danio rerio): quantitative inventory of genes, transcripts and proteins, and relation to egg quality. Fish physiology and biochemistry. 44(6):1509-1525

Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613

Eb-Levadoux, Y., Frelon, S., Simon, O., Arnaudguilhem, C., Lobinski, R., Mounicou, S. (2017) In vivo identification of potential uranium protein targets in zebrafish ovaries after chronic waterborne exposure. Metallomics : integrated biometal science. 9(5):525-534

Ribas, L., Liew, W.C., Díaz, N., Sreenivasan, R., Orbán, L., Piferrer, F. (2017) Heat-induced masculinization in domesticated zebrafish is family-specific and yields a set of different gonadal transcriptomes. Proceedings of the National Academy of Sciences of the United States of America. 114(6):E941-E950

Zhang, L., Jin, Y., Han, Z., Liu, H., Shi, L., Hua, X., A Doering, J., Tang, S., P Giesy, J., Yu, H. (2017) INTEGRATED IN SILICO AND IN VIVO APPROACHES TO INVESTIGATE EFFECTS OF BDE-99 MEDIATED BY THE NUCLEAR RECEPTORS ON DEVELOPING ZEBRAFISH. Environmental toxicology and chemistry. 37(3):780-787

Li, C., Tan, X.F., Lim, T.K., Lin, Q., Gong, Z. (2016) Comprehensive and quantitative proteomic analyses of zebrafish plasma reveals conserved protein profiles between genders and between zebrafish and human. Scientific Reports. 6:24329

Liu, Q., Klingler, R.H., Wimpee, B., Dellinger, M., King-Heiden, T., Grzybowski, J., Gerstenberger, S.L., Weber, D.N., Caravan, M.J. (2016) Maternal methylmercury from a wild-caught walleye diet induces developmental abnormalities in zebrafish. Reproductive toxicology (Elmsford, N.Y.). 65:272-282

Sohn, J., Kim, S., Koschorreck, J., Kho, Y., Choi, K. (2016) Alteration of sex hormone levels and steroidogenic pathway by several low molecular weight phthalates and their metabolites in male zebrafish (Danio rerio) and/or human adrenal cell (H295R) line. Journal of hazardous materials. 320:45-54

Zhang, W., Sheng, N., Wang, M., Zhang, H., Dai, J. (2016) Zebrafish reproductive toxicity induced by chronic perfluorononanoate exposure. Aquatic toxicology (Amsterdam, Netherlands). 175:269-276

Biava, P.M., Canaider, S., Facchin, F., Bianconi, E., Ljungberg, L., Rotilio, D., Burigana, F., Ventura, C. (2015) Stem Cell Differentiation Stage Factors from Zebrafish Embryo: A Novel Strategy to Modulate the Fate of Normal and Pathological Human (Stem) Cells. Current pharmaceutical biotechnology. 16:782-92

Liu, H., Tang, S., Zheng, X., Zhu, Y., Ma, Z., Liu, C., Hecker, M., Saunders, D.M., Giesy, J.P., Zhang, X., Yu, H. (2015) Bioaccumulation, biotransformation and toxicity of BDE-47, 6-OH-BDE-47 and 6-MeO-BDE-47 in early life-stages of zebrafish (Danio rerio). Environmental science & technology. 49(3):1823-33

Ma, Z., Yu, Y., Tang, S., Liu, H., Su, G., Xie, Y., Giesy, J.P., Hecker, M., Yu, H. (2015) Differential modulation of expression of nuclear receptor mediated genes by tris(2-butoxyethyl) phosphate (TBOEP) on early life stages of zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 169:196-203

Petushkova, N.A., Kuznetsova, G.P., Larina, O.V., Kisrieva, Y.S., Samenkova, N.F., Trifonova, O.P., Miroshnichenko, Y.V., Zolotarev, K.V., Karuzina, I.I., Ipatova, O.M., Lisitsa, A.V. (2015) One-dimensional proteomic profiling of Danio rerio embryo vitellogenin to estimate quantum dot toxicity. Proteome science. 13:17

Connolly, M.H., Dutkosky, R.M., Heah, T.P., Sayler, G.S., Henry, T.B. (2014) Temporal dynamics of oocyte growth and vitellogenin gene expression in zebrafish (danio rerio). Zebrafish. 11:107-14

Sreenivasan, R., Jiang, J., Wang, X., Bartfai, R., Kwan, H.Y., Christoffels, A., and Orban, L. (2014) Gonad Differentiation in Zebrafish Is Regulated by the Canonical Wnt Signaling Pathway. Biology of reproduction. 90(2):45

Hao, R., Bondesson, M., Singh, A.V., Riu, A., McCollum, C.W., Knudsen, T.B., Gorelick, D.A., and Gustafsson, J.Å. (2013) Identification of Estrogen Target Genes during Zebrafish Embryonic Development through Transcriptomic Analysis. PLoS One. 8(11):e79020

Liu, C., Wang, Q., Liang, K., Liu, J., Zhou, B., Zhang, X., Liu, H., Giesy, J.P., and Yu, H. (2013) Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae. Aquatic toxicology (Amsterdam, Netherlands). 128-129C:147-157

Sun, C., Hu, L., Liu, S., Gao, Z., and Zhang, S. (2013) Functional analysis of domain of unknown function (DUF) 1943, DUF1944 and von Willebrand factor type D domain (VWD) in vitellogenin2 in zebrafish. Developmental and comparative immunology. 41(4):469-476

Zheng, W., Xu, H., Lam, S.H., Luo, H., Karuturi, R.K., and Gong, Z. (2013) Transcriptomic analyses of sexual dimorphism of the zebrafish liver and the effect of sex hormones. PLoS One. 8(1):e53562

Cuello, S., Ximénez-Embún, P., Ruppen, I., Schonthaler, H.B., Ashman, K., Madrid, Y., Luque-Garcia, J.L., and Cámara, C. (2012) Analysis of protein expression in developmental toxicity induced by MeHg in zebrafish. The Analyst. 137(22):5302-5311

Lai, Y.S., Hsieh, F.J., and Hsu, T. (2012) Affinity isolation and mass spectral analysis of 1,10-phenanthroline (OP)-stimulated UV-damaged-DNA binding proteins expressed in zebrafish (Danio rerio) embryos. Fish physiology and biochemistry. 38(4):1117-1129

Levi, L., Ziv, T., Admon, A., Levavi-Sivan, B., and Lubzens, E. (2012) Insight into molecular pathways of retinal metabolism, associated with vitellogenesis in zebrafish. American journal of physiology. Endocrinology and metabolism. 302(6):E626-644

Meng, X., Bartholomew, C., and Craft, J.A. (2010) Differential expression of vitellogenin and oestrogen receptor genes in the liver of zebrafish, Danio Rerio. Analytical and bioanalytical chemistry. 396(2):625-630

Park, J.W., Henry, T.B., Menn, F.M., Compton, R.N., and Sayler, G. (2010) No bioavailability of 17α-ethinylestradiol when associated with nC₆₀ aggregates during dietary exposure in adult male zebrafish (Danio rerio). Chemosphere. 81(10):1227-1232

Finn, R.N., Kolarevic, J., Kongshaug, H., and Nilsen, F. (2009) Evolution and differential expression of a vertebrate vitellogenin gene cluster. BMC Evolutionary Biology. 9:2

Henry, T.B., McPherson, J.T., Rogers, E.D., Heah, T.P., Hawkins, S.A., Layton, A.C., and Sayler, G.S. (2009) Changes in the relative expression pattern of multiple vitellogenin genes in adult male and larval zebrafish exposed to exogenous estrogens. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 154(1):119-126

Kristoffersen, B.A., Nerland, A., Nilsen, F., Kolarevic, J., and Finn, R.N. (2009) Genomic and proteomic analyses reveal non-neofunctionalized vitellogenins in a basal clupeocephalan, the Atlantic herring, and point to the origin of maturational yolk proteolysis in marine teleosts. Mol. Biol. Evol.. 26(5):1029-1044

Wang, H., Tan, J.T., Emelyanov, A., Korzh, V., and Gong, Z. (2005) Hepatic and extrahepatic expression of vitellogenin genes in the zebrafish, Danio rerio. Gene. 356:91-100

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Wang, H., Yan, T., Tan, J.T., and Gong, Z. (2000) A zebrafish vitellogenin gene (vg3) encodes a novel vitellogenin without a phosvitin domain and may represent a primitive vertebrate vitellogenin gene. Gene. 256(1-2):303-310

Additional Citations (16):

Zebrafish Nomenclature Committee (2026) Nomenclature Data Curation (2026). Nomenclature Committee Submission.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Gaudet, P., Livstone, M.S., Lewis, S.E., Thomas, P.D. (2010) Annotation inferences using phylogenetic trees. Automated Data Submission. 12:449-62

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.