FIGURE

Fig. 6.

ID

ZDB-FIG-250804-43

Publication

Stark et al., 2025 - Morphogen gradients are regulated by porous media characteristics of the developing tissue

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Fig. 6.

Spatially varying sources and sinks in the 3D model at an exemplary time point at ≈60% epiboly. (A) Signed-distance function (SDF) of the embryo shell boundary, φ_shell, for an exemplary z-slice. Combining φ_shell (representing YSL and EVL boundaries) with φ_ECS enables the restriction of sources and sinks to the deep-cell surfaces. (B,C) A clipped model of the ECS showing that Fgf receptors (B, pink) are restricted to the deep cell boundaries, i.e. not the EVL or YSL. The sources (C, blue) are restricted to ≈5 rows of deep cells above the margin of the blastoderm. Receptor concentrations are given in units of nM; k_source is given in nM/s. Scale bars: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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