FIGURE

Fig. 6

ID

ZDB-FIG-250210-37

Publication

She et al., 2025 - The transcriptional repressor HEY2 regulates mitochondrial oxidative respiration to maintain cardiac homeostasis

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Fig. 6

Increased PPARGC1 and ESRRA alleviate mitochondrial and cardiac dysfunction due to Hey2 overexpression.a MitoTracker Red CMXRos staining measuring the mitochondrial mass of control AC16 or HEY2-OE AC16 cells transfected with control vectors, PPARGC1A or ESRRA vectors, as well as PPARGC1A and ESRRA plasmids together. Scale bar: 50?�m. b Quantification of MitoTracker Red fluorescent intensity of transfected HEY2-OE AC16 cells and control AC16 cells. Data were relative to fluorescent intensity in control group. n?=?38 (ctrl+vector, OE?+?PPARGC1A?+?ESRRA), n?=?41 (ctrl+PPARGC1A), n?=?39 (ctrl+ESRRA), n?=?43 (the rest groups). Box plots displayed median � interquartile range (IQR), with whiskers extending to the minimum and maximum values. *P?

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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