Fig. 6
|
mRpL4 regulates Notch signaling in the Drosophila wing A. Alignment of mRpL4 protein sequences from fly, human, mice, zebrafish and rat. The conserved residues are labeled with blue shadow. B. Representative images of wings (n > 15 wings) from flies expressing mRpL4 RNAi, UAS‐hmRpL4 and both under the control of nub‐Gal4. C. Representative images of wing imaginal disks (n > 10 wing disks) stained for Cut from flies expressing mRpL4 RNAi, UAS‐hmRpL4 and both under the control of nub‐Gal4. Representative regions showing Notch activity defects are marked by white arrow. D, E. Representative images of wing disks (n > 10 wing disks) bearing MARCM clones stained for Wg (D) and DHE (E). The MARCM clones are marked by GFP, and UAS‐hmRpL4 are expressed under the control of tub‐Gal4 in these clones. |