Fig. 1
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mRpL4 mutant leads to Notch signaling defects in the Drosophila wing A. Representative image of wings (n > 20 wings) from control adult flies, mRpL4K14608 heterozygous flies and flies harboring mRpL4K14608 homozygous mutant clones. B–D. Representative image of wing imaginal disks (n > 15 wing disks) stained for Cut and Wg, and wing disk expressing Notch signaling reporter NRE‐GFP, respectively. E, F. Representative images of wing disks (n > 10 wing disks) bearing MARCM clones stained for Wg. In (F), UAS‐mRpL4 are expressed under the control of tub‐Gal4 in the MARCM clones. Data information: The mRpL4K14608 mutant clones in these images are marked by the absence of RFP (B–D), while the MARCM clones are marked by GFP (E, F). Representative clones are marked by white arrows in (B–F). Scale bars = 100 μm. |