FIGURE

Fig. 6

ID

ZDB-FIG-240902-42

Publication

Arroyo et al., 2024 - Peds1 deficiency in zebrafish results in myeloid cell apoptosis and exacerbated inflammation

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Peds1a/b DKO line shows developmental delay, neutropenia, monocytopenia and exacerbated inflammation.

A Generation of a DKO line by whole deletion of peds1a and peds1b genes using CRISPR-Cas9. B–F Total plasmalogen and precursor quantification (B), larval length (C), number of neutrophil (D) and macrophage (E), and transcript levels of nfkb1, il1b, tnfa and clxcl8a genes, assayed by RT-qPCR (F). Each point represents one larva and the mean ± SEM of each group is also shown. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001. ROI region of interest, CHT caudal hematopoietic tissue.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Death Discov