FIGURE

Fig. 5

ID

ZDB-FIG-221119-39

Publication

Edmister et al., 2021 - A zebrafish model for calcineurin-dependent brain function

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Fig. 5

Fig. 5. Optomotor response (OMR). A) Response to moving red lines. B) Response to moving green lines. C) Response to moving blue lines. D) Response to red lines, moving 16x faster than the moving lines in A-C. Larvae were treated at 5 dpf with DMSO (2 μl/mL), cyclosporine (CsA, 10 μM), tacrolimus (FK506, 1 μM), rapamycin (RM, 1 μM), proINDY (5PI = 5 μM proINDY, 10PI = 10 μM proINDY), or a combination of two treatments. Differences between corresponding groups were examined for significance using a Chi-square test with a Bonferroni correction for multiple comparisons. N = 912, 372, 188, 263, 383, 275, 190, 178, 93 and 86 larvae in the 10 subsequent treatment groups. * p < 0.05/14, ** p < 0.01/14, *** p < 0.001/14.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: cyclosporin A chemical treatment by environment: cyclosporin A chemical treatment by environment: tacrolimus (anhydrous) chemical treatment by environment: tacrolimus (anhydrous) chemical treatment by environment: proINDY chemical treatment by environment: sirolimus
Observed In:	optomotor response
Stage:	Day 5

Phenotype Detail

Acknowledgments

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