| ZFIN ID: ZDB-EXP-230719-7 |
Experiment Conditions Description: chemical treatment by environment: tacrolimus (anhydrous), chemical treatment by environment: proINDY
| chemical treatment by environment: tacrolimus (anhydrous) |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | tacrolimus (anhydrous) |
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| Synonyms: | (-)-FK 506, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK 506, FK506, Prograf, tacrolimus, tacrolimus anhydrous |
| Definition: | A macrolide lactam containing a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. |
| Ontology: | ChEBI [CHEBI:61049] ( EBI ) |
| chemical treatment by environment: proINDY |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | proINDY |
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| Synonyms: | (1Z)-1-(5-acetoxy-3-ethyl-2(3H)-benzothiazoylidene)-2-propanone, (2Z)-3-ethyl-2-(2-oxopropylidene)-2,3-dihydro-1,3-benzothiazol-5-yl acetate, (Z)-3-ethyl-2-(2-oxopropylidene)-2,3-dihydrobenzo[d]thiazol-5-yl acetate, TG 007, TG-007, TG007 |
| Definition: | A member of the class of benzothiazoles that is 2,3-dihydro-1,3-benzothiazole substituted by 2-oxopropylidene, ethyl, and acetyloxy groups at positions 2, 3 and 5, respectively. It is the prodrug of INDY. |
| Ontology: | ChEBI [CHEBI:195315] ( EBI ) |
| Publication: | Edmister et al., 2021 |
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