FIGURE

Fig. 8

ID

ZDB-FIG-221119-42

Publication

Edmister et al., 2021 - A zebrafish model for calcineurin-dependent brain function

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Fig. 8

Fig. 8. Hierarchical cluster analysis of behavioral profiles. Behaviors at 5 dpf were analyzed in Cluster 3.0, using the Euclidian distance metric with complete linkage. The clusters were then color coded in TreeView using a spectrum from green (25 % decrease) to red (25 % increase). Three main clusters were identified, each with a distinct behavioral profile: 1) the calcineurin inhibitors FK506 and CsA, 2) DMSO and rapamycin (RM), and 3) the DYRK1A inhibitor ProINDY (PI) at two concentrations. Measurements behavior include activity in the first hour (1 h) and period 15 (P15), optomotor responses to moving lines in red (R), green (G), blue (B), fast red (FR) and all colors and speeds combined (RGB), startle response (S), habituation (Hab) and excitability (E).

Expression Data

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Antibody Labeling

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Behav. Brain Res.