ZFIN ID: ZDB-FIG-200624-11
Bian et al., 2019 - A knock-in strategy for editing human and zebrafish mitochondrial DNA using mito-CRISPR/Cas9 system. ACS synthetic biology   8(4):621-632 Full text @ ACS Synth Biol
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Long-pec
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
blm AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
brca2 AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
lig4 AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
mre11a AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
polg AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
prkdc AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
rad50 AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
rad54l AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
rpa1 AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
tfam AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
xrcc4 AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
xrcc5 AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
xrcc6 AB control Long-pec whole organism RTPCR
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + CRISPR1-br.dloop standard conditions Long-pec whole organism blm expression increased amount, abnormal
Long-pec whole organism brca2 expression increased amount, abnormal
Long-pec whole organism mre11a expression increased amount, abnormal
Long-pec whole organism polg expression increased amount, abnormal
Long-pec whole organism prkdc expression increased amount, abnormal
Long-pec whole organism rad50 expression increased amount, abnormal
Long-pec whole organism rad54l expression increased amount, abnormal
Long-pec whole organism rpa1 expression increased amount, abnormal
Long-pec whole organism tfam expression increased amount, abnormal
Long-pec whole organism xrcc4 expression increased amount, abnormal
Long-pec whole organism xrcc5 expression increased amount, abnormal
Long-pec whole organism xrcc6 expression increased amount, abnormal
Full text @ ACS Synth Biol