Gene

xrcc6

ID
ZDB-GENE-030131-6420
Name
X-ray repair complementing defective repair in Chinese hamster cells 6
Symbol
xrcc6 Nomenclature History
Previous Names
  • g22p1
  • Ku autoantigen
  • Ku70
  • wu:fi87b06
  • zgc:64131
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to contribute to double-stranded DNA binding activity. Involved in response to ionizing radiation. Predicted to localize to Ku70:Ku80 complex and nuclear chromosome, telomeric region. Is expressed in head; nervous system; neural keel; post-vent region; and presumptive neural retina. Orthologous to human XRCC6 (X-ray repair cross complementing 6).
Genome Resources
Note
None
Expression
All Expression Data
10 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 4 from Feitsma et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With xrcc6 Human Ortholog
No data available
Associated With xrcc6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002035 von Willebrand factor, type A
Domain IPR003034 SAP domain
Domain IPR005160 Ku70/Ku80 C-terminal arm
Domain IPR005161 Ku70/Ku80, N-terminal alpha/beta
Domain IPR006164 Ku70/Ku80 beta-barrel domain
Family IPR006165 Ku70
Homologous_superfamily IPR016194 SPOC-like, C-terminal domain superfamily
Homologous_superfamily IPR027388 Ku70, bridge and pillars domain superfamily
Homologous_superfamily IPR036361 SAP domain superfamily
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
Domain Details Per Protein
Protein Length Ku70 Ku70, bridge and pillars domain superfamily Ku70/Ku80 beta-barrel domain Ku70/Ku80 C-terminal arm Ku70/Ku80, N-terminal alpha/beta SAP domain SAP domain superfamily SPOC-like, C-terminal domain superfamily von Willebrand factor A-like domain superfamily von Willebrand factor, type A
UniProtKB:Q06IS3 610
UniProtKB:Q7T335 409
UniProtKB:A8KC26 610
UniProtKB:F1QZ60 610
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations