Gene
rad50
- ID
- ZDB-GENE-050506-110
- Name
- RAD50 homolog, double strand break repair protein
- Symbol
- rad50 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to contribute to 3'-5' exonuclease activity; DNA helicase activity; and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in several processes, including DNA duplex unwinding; chromosome organization involved in meiotic cell cycle; and telomere maintenance. Predicted to localize to Mre11 complex and chromosome. Human ortholog(s) of this gene implicated in transitional cell carcinoma. Orthologous to human RAD50 (RAD50 double strand break repair protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6906849 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Nijmegen breakage syndrome-like disorder | 613078 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DNA repair protein Rad50, eukaryotes | P-loop containing nucleoside triphosphate hydrolase | Rad50/SbcC-type AAA domain | RAD50, zinc hook |
|---|---|---|---|---|---|
|
UniProtKB:A0A8N7UW22
|
1312 |
Interactions and Pathways
No data available
Plasmids
No data available