FIGURE

Fig. 3

ID

ZDB-FIG-200302-56

Publication

Librán-Pérez et al., 2019 - Antiviral activity of palmitic acid via autophagic flux inhibition in zebrafish (Danio rerio)

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Fig. 3

Palmitic acid activates autophagy in zebrafish larvae. Zebrafish GFP-Lc3 transgenic embryos were treated with PA by bath immersion, and 24 h later, they were infected with SVCV for 24 h. The intensity of the GFP-Lc3 signal was measured in the body muscle mass (A) and liver (B). Numbers in the images represent the animals with the shown phenotype per the total number of animals analysed (C). The results are presented as the mean ± SEM of the analysed fish by treatment. Comparisons among groups were made using one-way ANOVA (multiple comparisons) followed by a Student-Newman-Keuls test. Significant differences are displayed as *** (0.0001 < p < 0.001), ** (0.001 < p < 0.01) or * (0.01 < p < 0.05).

Expression Data

Genes:	ambra1a atg5 becn1 gabarapa
Fish:	WT
Conditions:	chemical treatment by environment: hexadecanoic acid chemical treatment by environment: hexadecanoic acid, viral treatment by exposure to environment: Sprivivirus cyprinus viral treatment by exposure to environment: Sprivivirus cyprinus
Anatomical Term:	whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT zf155Tg
Conditions:	chemical treatment by environment: hexadecanoic acid chemical treatment by environment: hexadecanoic acid, viral treatment by exposure to environment: Sprivivirus cyprinus viral treatment by exposure to environment: Sprivivirus cyprinus
Observed In:	liver autophagic cell death muscle autophagic cell death whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Fish Shellfish Immunol.