ZFIN Fish: zf155Tg

ZFIN ID: ZDB-FISH-150901-4903

Fish name:	zf155Tg
Genotype:	zf155Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by zf155Tg
No data available

GENE EXPRESSION
Gene expression in zf155Tg

RNA expression

Expressed Gene	Structure	Conditions	Figures
map1lc3b	whole organism	control	Fig. 3, Fig. 6 from He et al., 2009
	whole organism	chemical treatment: sirolimus	Fig. 3, Fig. 6 from He et al., 2009

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab2-lamp1		neuromast hair cell lysosome	standard conditions	Fig. 3. from Santra et al., 2021
Ab1-map1lc3	map1lc3b	whole organism	control	Fig. 3, Fig. 6 from He et al., 2009
Ab1-map1lc3		whole organism	chemical treatment: sirolimus	Fig. 3, Fig. 6 from He et al., 2009

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
EGFP	caudal fin cell endothelial cell autophagosome (not) liver perinuclear region of cytoplasm muscle neuromast hair cell autophagosome spinal cord trunk autophagosome whole organism	control	11 figures from 8 publications
	caudal fin cell perinuclear region of cytoplasm endothelial cell autophagosome gut trunk autophagosome whole organism lysosome	chemical treatment by environment: trans-resveratrol	Fig. 5 from Al Azzaz et al., 2019 Fig 3 from Zhang et al., 2019 Fig. 7 from Espín-Palazón et al., 2016 Fig. 2 from Holland et al., 2016 Fig. 5 from Sasaki et al., 2014 Fig. 1 from van der Vaart et al., 2014 Fig. 5, Fig. 6 from He et al., 2009
	endothelial cell autophagosome lateral rectus regenerating tissue leukocyte whole organism	bacterial treatment	Fig. 7 from Espín-Palazón et al., 2016 Fig. 1 from Saera-Vila et al., 2016 Fig. 1 from van der Vaart et al., 2014 Fig. 4 from Mostowy et al., 2013

PHENOTYPE
Phenotype in zf155Tg

Phenotype	Conditions	Figures
autophagy increased occurrence, abnormal	viral treatment by exposure to environment: Sprivirus cyprinus	Fig. 7 from Espín-Palazón et al., 2016
autophagy increased occurrence, abnormal	chemical treatment by environment: sirolimus	Fig. 7 from Espín-Palazón et al., 2016
autophagy increased occurrence, abnormal	resection: lateral rectus	Fig. 1 from Saera-Vila et al., 2016
caudal fin EGFP expression increased amount, abnormal	chemical treatment by environment: bafilomycin A1	Fig 3 from Zhang et al., 2019
caudal fin EGFP expression increased distribution, abnormal	chemical treatment by environment: bafilomycin A1	Fig 3 from Zhang et al., 2019
gut EGFP expression increased amount, abnormal	chemical treatment by environment: trans-resveratrol	Fig. 5 from Al Azzaz et al., 2019
intestinal epithelial cell autophagosome increased amount, abnormal	chemical treatment: tunicamycin	Fig. 5 from Thakur et al., 2014
intestinal epithelial cell autophagy increased occurrence, abnormal	chemical treatment: tunicamycin	Fig. 5 from Thakur et al., 2014
intestinal epithelial cell positive regulation of autophagy in response to ER overload increased process quality, abnormal	chemical treatment: tunicamycin	Fig. 5 from Thakur et al., 2014
liver autophagosome decreased amount, abnormal	high cholesterol	Fig. 4 from Chen et al., 2018
liver autophagosome increased amount, abnormal	high fructose	Fig. 4 from Chen et al., 2018
liver autophagosome increased amount, abnormal	increased food availability	Fig. 4 from Chen et al., 2018
macroautophagy process quality, abnormal	chemical treatment: pharmaceutical	Fig. 5 from Sasaki et al., 2014
muscle autophagosome increased amount, abnormal	resection: lateral rectus	Fig. 1 from Saera-Vila et al., 2016
regenerating tissue autophagosome increased amount, abnormal	resection: lateral rectus	Fig. 1 from Saera-Vila et al., 2016
whole organism decreased life span, abnormal	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 1 from Masud et al., 2019
whole organism EGFP expression increased amount, abnormal	viral treatment by exposure to environment: Sprivirus cyprinus	Fig. 7 from Espín-Palazón et al., 2016
whole organism EGFP expression increased amount, abnormal	chemical treatment by environment: sirolimus	Fig. 7 from Espín-Palazón et al., 2016

CITATIONS (21)