Fig. 5
- ID
- ZDB-FIG-180912-56
- Publication
- Neelathi et al., 2018 - Cxcl12a induces snail1b expression to initiate collective migration and sequential Fgf-dependent neuromast formation in the zebrafish posterior lateral line primordium.
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Delayed Wnt Fgf signaling dynamics in the primordium of snail1b morphants. (A-C) Progressive restriction and eventual loss of lef1 expression in controls from 26 to 48?hpf. (D-F) Delayed restriction and persistent lef1 expression in snail1b morphants. (G-I) pea3 expression from 26 to 48?hpf in control embryos. (J-L) Delayed establishment and persistent trailing expression of pea3 expression in snail1b morphants. (M-O) cxcr4b expression from 26 to 48?hpf in control embryos. (P-R) Broad persistent cxcr4b expression in snail1b morphants. (S-U) cxcr7b expression from 26 to 48?hpf in control embryos. (V-X) Delayed establishment and persistent cxcr7b expression in snail1b morphants. (Y) Graph of length of the lef1 expression domain in control and snail1b-MO embryos plotted against the distance migrated by the pLL primordium. n=25 for each of two independent experiments if not stated in the text, n=147 and 144 for control and snail1b-MO for the data shown in Y. Dotted lines encircle pLL primordia. |
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Stage Range: | Prim-5 to Long-pec |
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Observed In: | |
Stage Range: | Prim-5 to Long-pec |