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ZIRC
ZFIN ID: ZDB-GENE-990415-71
Gene Name: ETS variant transcription factor 4
Gene Symbol: etv4    Nomenclature History

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Previous Names: etID309954.12 (1), pea3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Involved in limb morphogenesis; positive regulation of transcription, DNA-templated; and pronephric nephron tubule epithelial cell differentiation. Predicted to localize to the nucleus. Is expressed in several structures, including anterior neural rod; head; mesoderm; nervous system; and neural keel. Orthologous to human ETV4 (ETS variant transcription factor 4).
Genome Resources: Alliance (1),  Gene:30700 (1),  Ensembl(GRCz11):ENSDARG00000018303 (1)
GENE EXPRESSION
All Expression Data: 109 figures from 77 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2004 [MGC:76984]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3536 Point Mutation Unknown Premature Stop ENU
la010075Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011544Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018185Tg Transgenic Insertion Unknown Unknown DNA
    la018186Tg Transgenic Insertion Unknown Unknown DNA
    sa45463 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-etv4 N/A 3
    MO2-etv4 N/A 4
    MO3-etv4 N/A 4
    DISEASE ASSOCIATED WITH etv4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH etv4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA etv4-201 (1)    Ensembl 1957
    etv4-202 (1)    Ensembl 757
    etv4-203 (1)    Ensembl 789
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM etv4 No data available
    MARKER RELATIONSHIPS
    etv4 Contained in: [BAC] DKEY-69O7 (1) (order this)
    etv4 Encodes: [EST] fc19f01 (1)
    [cDNA] MGC:76984 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131425 (1) 1813 bp
    Genomic GenBank:AL833789 (1) 175664 bp
    Select Tool
    Polypeptide UniProtKB:F1RD02 (1) 494 aa
    Sequence Clusters UniGene:75840 (1)
    Sequence Information (all 27)
    ORTHOLOGY for etv4 ( Chr: 12 )
    CITATIONS (177)