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Fig. 5
Delayed Wnt Fgf signaling dynamics in the primordium of snail1b morphants. (A-C) Progressive restriction and eventual loss of lef1 expression in controls from 26 to 48 hpf. (D-F) Delayed restriction and persistent lef1 expression in snail1b morphants. (G-I) pea3 expression from 26 to 48 hpf in control embryos. (J-L) Delayed establishment and persistent trailing expression of pea3 expression in snail1b morphants. (M-O) cxcr4b expression from 26 to 48 hpf in control embryos. (P-R) Broad persistent cxcr4b expression in snail1b morphants. (S-U) cxcr7b expression from 26 to 48 hpf in control embryos. (V-X) Delayed establishment and persistent cxcr7b expression in snail1b morphants. (Y) Graph of length of the lef1 expression domain in control and snail1b-MO embryos plotted against the distance migrated by the pLL primordium. n=25 for each of two independent experiments if not stated in the text, n=147 and 144 for control and snail1b-MO for the data shown in Y. Dotted lines encircle pLL primordia.