FIGURE

Fig. 6

ID

ZDB-FIG-180119-23

Publication

Schwarzer et al., 2017 - Dlx3b/4b is required for early-born but not later-forming sensory hair cells during zebrafish inner ear development

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Fig. 6

OEPD-dependent neurogenesis in dlx3b/4b-deficient embryos. (A,B) Expression of neurod1 (blue) in control siblings and dlx3b/4b mutants at 24 hpf. Expression of stm (red) reveals the size reduction of the otic vesicle in dlx3b/4b mutants in comparison with wild-type embryos. (C,D) Expression of neurog1 in control and dlx3b/4b mutant embryos at 24 hpf. (E,F) Double staining of neurod1 (red) and tlx3b (blue) indicates increased production of anterior lateral line ganglion progenitors in dlx3b/4b mutants compared to control siblings at 24 hpf. (G,H) At 32 hpf, phox2a expression in dlx3b/4b mutants is indistinguishable from wild-type controls. (A,B,E,F) Lateral views with anterior to the left. (C,D,G,H) Dorsal views with anterior to the left. gALL, anterior lateral line ganglion progenitor; gVII, geniculate ganglion progenitor; gVIII, statoacoustic ganglion progenitor; gIX, petrosal ganglion progenitor; gX, nodose ganglion progenitor. Scale bar: 40 µm.

Expression Data

Genes:	neurod1 neurog1 phox2a stm tlx3b
Fish:	AB Df(Chr12:dlx3b, dlx4b)tud70/tud70 (AB)
Anatomical Terms:	anterior lateral line ganglion facial ganglion glossopharyngeal ganglion neurogenic placode neuroblast otic epithelium otic vesicle vagal ganglion
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	Df(Chr12:dlx3b, dlx4b)tud70/tud70 (AB)
Observed In:	anterior lateral line ganglion neurogenic placode neuroblast otic epithelium otic vesicle
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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