Gene

tlx3b

ID
ZDB-GENE-021021-1
Name
T cell leukemia homeobox 3b
Symbol
tlx3b Nomenclature History
Previous Names
  • tlx3
  • ztlx-3b (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in animal organ development and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in cranial ganglion; neurons; and trigeminal placode. Orthologous to human TLX3 (T cell leukemia homeobox 3).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tlx3b Human Ortholog
No data available
Associated With tlx3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Family IPR042247 T-cell leukemia homeobox protein 1/2/3
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily T-cell leukemia homeobox protein 1/2/3
UniProtKB:Q8JI11 300
UniProtKB:F1QSY0 300
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations