ZFIN ID: ZDB-GENE-990415-235
Gene Name: recombination activating gene 2
Gene Symbol: rag2
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:136743

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 11 publications
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fb101 Indel Unknown Frameshift ZINC_FINGER_NUCLEASE
sa44245 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH rag2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Omenn syndrome Omenn syndrome 603554
    severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive Severe combined immunodeficiency, B cell-negative 601457
    Combined cellular and humoral immune defects with granulomas 233650
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process V(D)J recombination (more)
    Cellular Component DNA recombinase complex (more)
    Molecular Function protein binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004321 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR011043 (1)
  • InterPro:IPR015915 (1)
  • InterPro:IPR025162 (1)
  • Pfam:PF03089 (1)
  • Pfam:PF13341 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rag2-001 (1) 2682
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM rag2
    MARKER RELATIONSHIPS
    rag2Contained in: [BAC] CH211-256A21 (1) (order this)
    rag2Encodes: [EST] fc85e11 (1)
    [cDNA] MGC:136743 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131385 (1) 2635bp
    Genomic GenBank:AL935203 (1) 163572bp
    Select Tool
    Polypeptide UniProtKB:O13034 (1) 530aa
    Sequence Clusters UniGene:79818 (1)
    Sequence Information (all 18)
    OTHER rag2 GENE PAGES
  • Alliance (1)
  • Gene:30658 (1)
  • VEGA:OTTDARG00000022572 (1)
  • Ensembl(GRCz10):ENSDARG00000052121 (1)
  • ORTHOLOGY for rag2 (Chr: 25)
    CITATIONS (74)