ZFIN ID: ZDB-GENE-990415-235
Gene Name: recombination activating gene 2
Gene Symbol: rag2
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:136743

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 11 publications
Wild-type Stages, Structures: Pharyngula:Prim-25 (36.0h-42.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fb101 Indel Unknown Frameshift ZINC_FINGER_NUCLEASE
sa44245 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH rag2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Omenn syndrome Omenn syndrome 603554
    severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive Severe combined immunodeficiency, B cell-negative 601457
    Combined cellular and humoral immune defects with granulomas 233650
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein-DNA complex assembly (more)
    Cellular Component DNA recombinase complex (more)
    Molecular Function protein binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004321 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR011043 (1)
  • InterPro:IPR015915 (1)
  • InterPro:IPR025162 (1)
  • Pfam:PF03089 (1)
  • Pfam:PF13341 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA rag2-001 (1) 2682
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM rag2
    MARKER RELATIONSHIPS
    rag2Contained in: [BAC] CH211-256A21 (1) (order this)
    rag2Encodes: [EST] fc85e11 (1)
    [cDNA] MGC:136743 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131385 (1) 2635bp
    Genomic GenBank:AL935203 (1) 163572bp
    Select Tool
    Polypeptide UniProtKB:O13034 (1) 530aa
    Sequence Clusters UniGene:79818 (1)
    Sequence Information (all 18)
    OTHER rag2 GENE PAGES
  • Alliance (1)
  • Gene:30658 (1)
  • VEGA:OTTDARG00000022572 (1)
  • Ensembl(GRCz11):ENSDARG00000052121 (1)
  • ORTHOLOGY for rag2 (Chr: 25)
    CITATIONS (77)