FIGURE

Fig. 7 S1

ID

ZDB-FIG-170310-13

Publication

Bloomekatz et al., 2017 - Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly

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Fig. 7 S1

Expression of genes encoding Pdgfra ligands.

(A–C) Dorsal views, anterior to the top, display expression of pdgfaa (A), pdgfab (B), and pdgfc (C) in wt embryos at 14 s. Since Pdgfa homodimers and Pdgfc homodimers have been shown to interact with Pdgfra (Andrae et al., 2008), we chose to examine the expression of the two zebrafish Pdgfa homologs, pdgfaa and pdgfab, as well as the expression of pdgfc (Eberhart et al., 2008). Both pdgfaa (A) and pdgfab (B) are expressed in bilateral medial stripes (arrows, A), consistent with the location of the anterior endoderm. We detected pdgfc (C) expression in the otic vesicles and somites at 14 s, but we did not detect expression over background levels within the anterior endoderm. Scale bar: 60 μm.

Expression Data

Genes:	pdgfaa pdgfab pdgfc
Fish:	WT
Anatomical Terms:	endoderm anterior region otic vesicle
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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