Gene

pdgfab

ID
ZDB-GENE-060929-124
Name
platelet-derived growth factor alpha polypeptide b
Symbol
pdgfab Nomenclature History
Previous Names
  • wu:fc32c12
  • zgc:153249
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have platelet-derived growth factor receptor binding activity. Predicted to be involved in several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of intracellular signal transduction; and positive regulation of protein autophosphorylation. Predicted to localize to extracellular space. Is expressed in endoderm; mouth; pharyngeal arch; pharyngeal endoderm; and pharyngeal pouch. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pdgfab Human Ortholog
No data available
Associated With pdgfab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023581 Platelet-derived growth factor, conserved site
Domain IPR000072 PDGF/VEGF domain
Domain IPR006782 Platelet-derived growth factor, N-terminal
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine PDGF/VEGF domain Platelet-derived growth factor, conserved site Platelet-derived growth factor, N-terminal
UniProtKB:Q08CD2 230
UniProtKB:A0A0R4IHM5 55
UniProtKB:A0A0R4IXE1 230
UniProtKB:A0A2R8QN29 230
UniProtKB:A0A0R4IF94 47
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations