Gene

pdgfaa

ID
ZDB-GENE-030918-2
Name
platelet-derived growth factor alpha polypeptide a
Symbol
pdgfaa Nomenclature History
Previous Names
  • pdgfa
  • Platelet-derived growth factor A (1)
  • zgc:100777
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have platelet-derived growth factor receptor binding activity. Involved in cardiac muscle progenitor cell migration to the midline involved in heart field formation and neural crest cell migration. Predicted to localize to extracellular space. Is expressed in several structures, including anterior neural keel; chordo neural hinge; diencephalon; endoderm; and head. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pdgfaa Human Ortholog
No data available
Associated With pdgfaa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023581 Platelet-derived growth factor, conserved site
Domain IPR000072 PDGF/VEGF domain
Domain IPR006782 Platelet-derived growth factor, N-terminal
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine PDGF/VEGF domain Platelet-derived growth factor, conserved site Platelet-derived growth factor, N-terminal
UniProtKB:Q6DC06 194
UniProtKB:Q9DE50 195
UniProtKB:A5PMP7 194
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations