Gene
pdgfaa
- ID
- ZDB-GENE-030918-2
- Name
- platelet-derived growth factor alpha polypeptide a
- Symbol
- pdgfaa Nomenclature History
- Previous Names
-
- pdgfa
- Platelet-derived growth factor A (1)
- zgc:100777
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable platelet-derived growth factor receptor binding activity. Involved in angiogenesis. Acts upstream of or within with a positive effect on neural crest cell migration. Acts upstream of or within cardiac muscle progenitor cell migration to the midline involved in heart field formation. Predicted to be located in extracellular region and membrane. Predicted to be active in extracellular space. Is expressed in several structures, including anterior neural keel; chordo neural hinge; diencephalon; endoderm; and head. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 24 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu754 (15 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine-knot cytokine | PDGF/VEGF domain | Platelet-derived growth factor, conserved site | Platelet-derived growth factor, N-terminal |
|---|---|---|---|---|---|---|
| UniProtKB:A5PMP7 | InterPro | 194 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pdgfaa-202
(1)
|
Ensembl | 1,464 nt |
Interactions and Pathways
No data available
Plasmids
No data available